3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose

Base Information

• Chemical Name: 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose
• CAS No.: 1037492-35-5
• Molecular Formula: C₃₆H₄₀O₇P₂
• Molecular Weight: 646.657
• Mol file: 1037492-35-5.mol

Synonyms:3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose

Chemical Property of 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose

There total 1 articles about 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.8%

bis(2-methoxyphenyl)phosphine (10177-79-4) + 1,2-O-isopropylidene-3,5-di-O-(trifluoromethanesulfonyl)-α-D-ribofuranose (250130-88-2) → 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose (1037492-35-5)

Guidance literature:

bis(2-methoxyphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; at 20 ℃; for 1h;

1,2-O-isopropylidene-3,5-di-O-(trifluoromethanesulfonyl)-α-D-ribofuranose; In tetrahydrofuran; at 20 ℃; for 3h; Further stages.;

DOI:10.1039/b719748a

Reference yield: 76.0%

chloromethyl(1,5-cyclooctadiene)palladium(II) + 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose (1037492-35-5) → [PdClMe(3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose)]

Guidance literature:

In dichloromethane; under N2; to a deaerated soln. of a ligand (0.18 mmol) in CH2Cl2 was added a deaerated soln. of Pd-contg. compd. (0.15 mmol) in CH2Cl2; stirringat room temp. for 0.5 h; the soln. was concd. to half of its original vol.; Et2O addn.; ppt. was filtered off, washed with Et2O and dried in a sream of N2; elem. anal.;

DOI:10.1039/b719748a

Reference yield: 73.5%

dichloro(1,5-cyclooctadiene)palladium(II) (12107-56-1) + 3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose (1037492-35-5) → [PdCl2(3,5-dideoxy-1,2-O-isopropylidene-3,5-bis(di(2-methoxyphenyl)phosphanyl)-α-D-xylofuranose)]

Guidance literature:

In dichloromethane; under N2; to a deaerated soln. of a ligand (0.34 mmol) in CH2Cl2 was added a deaerated soln. of Pd-contg. compd. (0.32 mmol) in CH2Cl2; stirringat room temp. for 1 h; the soln. was concd. to half of its original vol.; Et2O addn.; ppt. was filtered off, washed with Et2O and dried in a sream of N2; elem. anal.;

DOI:10.1039/b719748a

upstream raw materials:

bis(2-methoxyphenyl)phosphine

1,2-O-isopropylidene-3,5-di-O-(trifluoromethanesulfonyl)-α-D-ribofuranose