5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol

Base Information

• Chemical Name: 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol
• CAS No.: 943519-41-3
• Molecular Formula: C₃₆H₄₀N₄O₄
• Molecular Weight: 592.738

Synonyms:5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol

Chemical Property of 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol

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Technology Process of 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol

There total 17 articles about 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

2,4-bisbenzyloxy-5-isopropyl-N-[4-methoxy-3-(methyl(propyl)amino)phenyl]benzamide (943519-40-2) → 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol (943519-41-3)

Guidance literature:

2,4-bisbenzyloxy-5-isopropyl-N-[4-methoxy-3-(methyl(propyl)amino)phenyl]benzamide; With Lawessons reagent; In toluene; at 110 ℃; for 3h;

With hydrazine; In 1,4-dioxane; at 80 ℃; for 0.5h;

With 1,1'-carbonyldiimidazole; In ethyl acetate; for 3h; Heating / reflux;

Reference yield: 33.0%

2,4-bisbenzyloxy-5-isopropyl-N-[4-methoxy-3-(methyl(propyl)amino)phenyl]benzamide (943519-40-2) + 1,1'-carbonyldiimidazole (530-62-1) → 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol (943519-41-3)

Guidance literature:

2,4-bisbenzyloxy-5-isopropyl-N-[4-methoxy-3-(methyl(propyl)amino)phenyl]benzamide; With Lawessons reagent; In toluene; at 110 ℃; for 3h;

With hydrazine; In 1,4-dioxane; at 80 ℃; for 0.5h;

1,1'-carbonyldiimidazole; In ethyl acetate; for 3h; Heating / reflux;

Reference yield:

C35H42N4O3 (959687-60-6) → 5-(2,4-bisbenzyloxy-5-isopropylphenyl)-4-[4-methoxy-3-(methyl(propyl)amino)phenyl]-4H-[1,2,4]triazol-3-ol (943519-41-3)

Guidance literature:

With 1,1'-carbonyldiimidazole; In ethyl acetate; for 3h; Heating / reflux;

upstream raw materials:

2,4-bisbenzyloxy-5-isopropyl-N-[4-methoxy-3-(methyl(propyl)amino)phenyl]benzamide

C₃₅H₄₂N₄O₃

1,1'-carbonyldiimidazole

2,4-dihydroxy-5-isopropylbenzoic acid methyl ester

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