(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

Base Information

Chemical Name:(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone
CAS No.:1420181-00-5
Molecular Formula:C₂₆H₃₃NO₅
Molecular Weight:439.552
Hs Code.:

Synonyms:(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

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Chemical Property of (5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

Chemical Property:

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Technology Process of (5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

There total 2 articles about (5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1420181-01-6
(2-butyl-5-nitro-1-benzofuran-3-yl)[4-(3,3-diethoxypropoxy)phenyl]methanone

: 1420181-00-5
(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 50 ℃; for 4h; under 7500.75 Torr;

Reference yield:

: 35573-93-4
3-chloro-1,1-diethoxy-propane

: 1420181-00-5
(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; sodium iodide / 6 h / Reflux

2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 50 °C / 7500.75 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; sodium iodide; In methanol;

Reference yield:

: 1420181-00-5
(5-amino-2-butyl-benzofuran-3-yl)[4'-(3,3-diethoxypropoxy)phenyl]methanone

: 141626-36-0
dronedarone

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / dichloromethane / 2.5 h / 30 - 35 °C

2: sulfuric acid / tetrahydrofuran; water / 2 h / 50 °C

3: hydrogen / methanol / 4 h / 50 °C / 7500.75 Torr

With pyridine; sulfuric acid; hydrogen; In tetrahydrofuran; methanol; dichloromethane; water;