4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride

Base Information

• Chemical Name: 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride
• CAS No.: 97376-33-5
• Molecular Formula: C₁₅H₁₅N₅*ClH
• Molecular Weight: 301.779
• Mol file: 97376-33-5.mol

Synonyms:4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride

Chemical Property of 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride

There total 4 articles about 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.3%

benzaldehyde (100-52-7) + aniline (62-53-3) + N-Cyanoguanidine (127099-85-8,780722-26-1,461-58-5) → 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride (97376-33-5)

Guidance literature:

With hydrogenchloride; microwave irradiation;

DOI:10.1016/j.bmcl.2004.12.049

Reference yield:

dicyandiamide (127099-85-8,780722-26-1) + benzaldehyde (100-52-7) + aniline (62-53-3) → 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride (97376-33-5)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 140 ℃; for 0.833333h; Microwave irradiation;

DOI:10.1021/acscombsci.9b00079

Reference yield:

aniline (62-53-3) → 4,6-diamino-1,2-dihydro-1,2-diphenyl-1,3,5-triazine hydrochloride (97376-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water / 0.17 h / 170 °C

2: hydrogenchloride / water; methanol / 4 h / Reflux

With hydrogenchloride; In methanol; water;

DOI:10.1021/acsinfecdis.8b00358

upstream raw materials:

benzaldehyde

aniline

N-Cyanoguanidine

1-phenylbiguanide monohydrochloride

Downstream raw materials:

N²,6-diphenyl-1,3,5-triazine-2,4-diamine