methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

Base Information

• Chemical Name: methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside
• CAS No.: 216577-81-0
• Molecular Formula: C₂₄H₃₀O₈
• Molecular Weight: 446.497
• Mol file: 216577-81-0.mol

Synonyms:methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

Chemical Property of methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

There total 1 articles about methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl 2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside (134039-09-1) + acetic acid (64-19-7,77671-22-8) → methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside (216577-81-0)

Guidance literature:

With toluene-4-sulfonic acid; Triethyl orthoacetate; triethylamine; In water; toluene;

DOI:10.1080/07328309808001891

Reference yield: 60.0%

methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside (216577-81-0) → methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-xylo-hexopyranosyl-3-ulose (216577-87-6)

Guidance literature:

With tetrapropylammonium perruthennate; 4 A molecular sieve; 4-methylmorpholine N-oxide; In dichloromethane;

DOI:10.1080/07328309808001891

Reference yield:

methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside (216577-81-0) → methyl 2,6-di-O-benzyl-5-C-methoxy-β-D-gulopyranoside (216577-78-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / pyridine

2: 67 percent / toluene / 68 h / 20 °C

3: 76 percent / MeONa / methanol / 15 h / 20 °C

With sodium methylate; In pyridine; methanol; toluene; 1: Esterification / 2: Substitution / 3: Hydrolysis;

DOI:10.1080/07328309808001891

upstream raw materials:

methyl 2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

acetic acid

Downstream raw materials:

methyl 4-O-acetyl-2,6-di-O-benzyl-5-C-methoxy-β-D-xylo-hexopyranosyl-3-ulose

methyl 2,6-di-O-benzyl-5-C-methoxy-β-D-galactopyranoside

methyl 2,6-di-O-benzyl-5-C-methoxy-β-D-gulopyranoside

methyl 4-O-acetyl-3-O-benzoyl-2,6-di-O-benzyl-5-C-methoxy-β-D-gulopyranoside