3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine

Base Information

• Chemical Name: 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine
• CAS No.: 318293-18-4
• Molecular Formula: C₁₆H₁₃N₅O₂S
• Molecular Weight: 339.378
• Mol file: 318293-18-4.mol

Synonyms:3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine

Chemical Property of 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine

There total 1 articles about 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-Hydroxy-8-methyl-6-phenyl-6H-pyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carboxylic acid methyl ester (178269-05-1) → 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine (318293-18-4)

Guidance literature:

With hydrazine hydrate; In ethanol; for 25h; Heating;

DOI:10.1016/S0928-0987(00)00102-0

Reference yield: 95.0%

benzaldehyde (100-52-7) + 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine (318293-18-4) → (Z)-benzylidene 3-hydroxy-8-methyl-6-phenylpyrazolo[4,3-b]thieno[2,3-d]pyridine-2-carbohydrazine

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; for 0.75h;

DOI:10.1016/S0928-0987(00)00102-0

Reference yield: 89.0%

4-bromo-benzaldehyde (1122-91-4) + 3-hydroxy-8-methyl-6-phenylpyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carbohydrazine (318293-18-4) → (Z)-(4'-bromobenzylidene) 3-hydroxy-8-methyl-6-phenylpyrazolo[4,3-b]thieno[2,3-d]pyridine-2-carbohydrazine

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; for 0.75h;

DOI:10.1016/S0928-0987(00)00102-0

upstream raw materials:

3-Hydroxy-8-methyl-6-phenyl-6H-pyrazolo[3,4-b]thieno[2,3-d]pyridine-2-carboxylic acid methyl ester