6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID

Base Information

• Chemical Name: 6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID
• CAS No.: 874493-62-6
• Molecular Formula: C₈H₆N₄O₃
• Molecular Weight: 206.161
• Mol file: 874493-62-6.mol

Synonyms:Pyrido[2,3-b]pyrazine-2-carboxylicacid, 6-amino-3-hydroxy- (5CI)

Chemical Property of 6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID

Chemical Property:

• PSA: 122.69000
• LogP: -0.47140

Purity/Quality:

97% ^*data from raw suppliers

6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID

There total 1 articles about 6-AMINO-3-HYDROXY-PYRIDO[2,3-B]PYRAZINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-diamino-3-nitrosopyridine (89323-10-4) + diethyl malonate (105-53-3) → 6-amino-3-oxo-3,4-dihydro-pyrido[2,3-b]pyrazine-2-carboxylic acid (874493-62-6)

Guidance literature:

With sodium ethanolate;

DOI:10.1039/jr9550000303 DOI:10.1039/jr9550002032

Reference yield:

6-amino-3-oxo-3,4-dihydro-pyrido[2,3-b]pyrazine-2-carboxylic acid (874493-62-6) → 6-amino-4H-pyrido[2,3-b]pyrazin-3-one (874493-61-5)

Guidance literature:

at 300 ℃;

DOI:10.1039/jr9550000303 DOI:10.1039/jr9550002032

upstream raw materials:

2,6-diamino-3-nitrosopyridine

diethyl malonate

Downstream raw materials:

6-amino-4H-pyrido[2,3-b]pyrazin-3-one