tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate

Base Information

• Chemical Name: tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate
• CAS No.: 944920-05-2
• Molecular Formula: C₂₉H₄₆N₄O₇S₂
• Molecular Weight: 626.839
• Mol file: 944920-05-2.mol

Synonyms:tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate

Chemical Property of tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate

There total 1 articles about tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 6-oxohexylcarbamate (80860-42-0) + [Cy3B]-N-Demethyldofetilide (176447-94-2) → tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate (944920-05-2)

Guidance literature:

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1021/jm0700565

Reference yield:

tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate (944920-05-2) → C55H68N6O10S3*CF3CO2H

Guidance literature:

Multi-step reaction with 2 steps

1: 0.08 h / 20 °C

2: 86 percent / diisopropylethylamine / dimethylformamide / 0.08 h

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

DOI:10.1021/jm0700565

Reference yield:

tert-butyl 6-((4-(methylsulfonamido)phenethyl)(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)hexylcarbamate (944920-05-2) → [2-(6-{[2-(4-methanesulfonylaminophenoxy)ethyl][2-(4-methanesulfonylaminophenyl)ethyl]amino}hexylcarbamoyl)ethyl]carbamic acid tert-butyl ester trifluoroacetate

Guidance literature:

Multi-step reaction with 2 steps

1: 0.08 h / 20 °C

2: 65 percent / diisopropylethylamine; [2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium]*PF₆ / 1-methyl-pyrrolidin-2-one

With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one;

DOI:10.1021/jm0700565

upstream raw materials:

tert-butyl 6-oxohexylcarbamate

[Cy₃B]-N-Demethyldofetilide