tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate

Base Information

• Chemical Name: tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate
• CAS No.: 329354-05-4
• Molecular Formula: C₁₇H₂₅NO₄SSi
• Molecular Weight: 367.541
• Mol file: 329354-05-4.mol

Synonyms:tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate

Chemical Property of tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate

There total 2 articles about tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide (18303-04-3) + phenyl(trimethylsilylethynyl)iodonium triflate (133816-00-9) → tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate (329354-05-4)

Guidance literature:

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide; With n-butyllithium; In toluene; at 0 ℃;

phenyl(trimethylsilylethynyl)iodonium triflate; In toluene;

Reference yield: 46.0%

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide (18303-04-3) + phenyl(trimethylsilylethynyl)iodonium triflate (133816-00-9) → tert-butyl ethynyl[(4-methylphenyl)sulfonyl]carbamate (329354-01-0) + tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate (329354-05-4)

Guidance literature:

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide; With potassium hexamethylsilazane; In toluene; at 0 - 20 ℃;

phenyl(trimethylsilylethynyl)iodonium triflate; In toluene; at 20 ℃; Further stages.;

DOI:10.1055/s-2007-982562

Reference yield: 67.0%

tert-butyl (4-methylphenyl)sulfonyl[(trimethylsilyl)ethynyl]carbamate (329354-05-4) → 3-[(4-methylphenyl)sulfonyl]-5-(trimethylsilyl)-1,3-oxazol-2(3H)-one

Guidance literature:

[Ph₃PAuNTf₂]; In chloroform-d1; at 20 ℃;

DOI:10.1055/s-2007-982562

upstream raw materials:

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide

phenyl(trimethylsilylethynyl)iodonium triflate