4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide

Base Information

• Chemical Name: 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide
• CAS No.: 1384872-17-6
• Molecular Formula: C₄₀H₃₆N₂O₁₀S₄
• Molecular Weight: 832.997
• Mol file: 1384872-17-6.mol

Synonyms:4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide

Chemical Property of 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide

There total 2 articles about 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

sodium methylate (124-41-4) + 2,2-dichloro-2,2a-dihydro-5,6-dimethoxy-1H,8H-2a-(4-methoxyphenyl)azeto[2,1-b][1,3]benzothiazin-1-one → 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide (1384872-17-6) + 2,3-Dimethoxy-7-(4-methoxy-phenyl)-8,9-dihydro-5-thia-8-aza-benzocycloheptene-6-carboxylic acid methyl ester (97326-07-3)

Guidance literature:

In methanol; for 3h; Reflux;

DOI:10.1016/j.tet.2012.05.033

Reference yield:

6,7-dimethoxy-2-(p-methoxyphenyl)-4H-1,3-benzothiazine (65448-22-8) → 4,4',5,5'-tetramethoxy-{2,2'-di-[5-methoxycarbonyl-4-(4-methoxyphenyl)-2-thiazolyl]}-diphenyl disulfide (1384872-17-6) + 2,3-Dimethoxy-7-(4-methoxy-phenyl)-8,9-dihydro-5-thia-8-aza-benzocycloheptene-6-carboxylic acid methyl ester (97326-07-3)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 1 h / Reflux

2: methanol / 3 h / Reflux

In methanol; toluene; 1: Staudinger reaction;

DOI:10.1016/j.tet.2012.05.033

upstream raw materials:

6,7-dimethoxy-2-(p-methoxyphenyl)-4H-1,3-benzothiazine

sodium methylate