Octahydropyrazino[1,2-a]azepine-3,4-dione

Base Information

Chemical Name:Octahydropyrazino[1,2-a]azepine-3,4-dione
CAS No.:88327-64-4
Molecular Formula:C₉H₁₄N₂O₂
Molecular Weight:182.222
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80523585
Mol file:88327-64-4.mol

Synonyms:88327-64-4;Octahydropyrazino[1,2-a]azepine-3,4-dione;DTXSID80523585;PYRAZINO[1,2-A]AZEPINE-3,4-DIONE, OCTAHYDRO- (9CI);1,2,6,7,8,9,10,10a-octahydropyrazino[1,2-a]azepine-3,4-dione

Suppliers and Price of Octahydropyrazino[1,2-a]azepine-3,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
octahydro-Pyrazino[1,2-a]azepine-3,4-dione 97.00%
5G
$ 3590.00

AccelPharmtech
octahydro-Pyrazino[1,2-a]azepine-3,4-dione 97.00%
1G
$ 2100.00

Total 3 raw suppliers

Chemical Property of Octahydropyrazino[1,2-a]azepine-3,4-dione

Chemical Property:

PSA：49.41000
LogP:0.15410
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:182.105527694
Heavy Atom Count:13
Complexity:240

Purity/Quality:: octahydro-Pyrazino[1,2-a]azepine-3,4-dione 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2CNC(=O)C(=O)N2CC1

Technology Process of Octahydropyrazino[1,2-a]azepine-3,4-dione

There total 3 articles about Octahydropyrazino[1,2-a]azepine-3,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 42839-32-7
2-aminomethyl-2,3,4,5,6,7-hexahydro-1H-azepine

: 95-92-1
oxalic acid diethyl ester

: 88327-64-4
2,3-dioxo-1,4-diazabicyclo<4.5.0>undecane

Guidance literature:: Heating;

Reference yield:

: 13414-33-0
7-ethoxy-3,4,5,6-tetrahydro-2H-azepine

: 88327-64-4
2,3-dioxo-1,4-diazabicyclo<4.5.0>undecane

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / 20 h / 140 - 145 °C

2: 79 percent / LiAlH₄ / tetrahydrofuran / 24 h / Heating

3: 70 percent / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran;

Reference yield:

: 64480-12-2
2-nitromethylene-2,3,4,5,6,7-hexahydro-1H-azepine

: 88327-64-4
2,3-dioxo-1,4-diazabicyclo<4.5.0>undecane

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / LiAlH₄ / tetrahydrofuran / 24 h / Heating

2: 70 percent / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran;