Technology Process of 8-((4-methoxybenzyl)oxy)octanal
There total 5 articles about 8-((4-methoxybenzyl)oxy)octanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; sulfur trioxide pyridine complex; triethylamine;
In
dichloromethane; dimethyl sulfoxide;
at 0 - 20 ℃;
for 5.5h;
DOI:10.1021/ol3017676
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Cooling with ice
1.2: 2.5 h / Cooling with ice
2.1: sodium hydrogencarbonate / sodium hypochlorite; potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 2 h / 20 °C
With
sodium hydride; sodium hydrogencarbonate;
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide;
In
dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran; dimethyl sulfoxide; mineral oil / 1 h / 0 °C
1.2: 18 h / 0 - 20 °C
2.1: pyridine; sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 5.5 h / 0 - 20 °C
With
pyridine; sulfur trioxide pyridine complex; sodium hydride; triethylamine;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; mineral oil;
2.1: Parikh-Doering oxidation;
DOI:10.1021/ol3017676
