Phenyl quinolin-8-ylcarbamate

Base Information

• Chemical Name: Phenyl quinolin-8-ylcarbamate
• CAS No.: 83848-82-2
• Molecular Formula: C16H12 N2 O2
• Molecular Weight: 264.283
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID20462742
• Wikidata: Q82287325
• Mol file: 83848-82-2.mol

Synonyms:Phenyl quinolin-8-ylcarbamate;83848-82-2;SCHEMBL2398063;DTXSID20462742;AKOS008917835;PHENYL-N-(8-QUINOLYL)CARBAMATE

Chemical Property of Phenyl quinolin-8-ylcarbamate

Chemical Property:

• PSA: 54.71000
• LogP: 3.85930
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 264.089877630
• Heavy Atom Count: 20
• Complexity: 328

Purity/Quality:

98%min ^*data from raw suppliers

PHENYL-N-(8-QUINOLYL)CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC(=O)NC2=CC=CC3=C2N=CC=C3

Technology Process of Phenyl quinolin-8-ylcarbamate

There total 2 articles about Phenyl quinolin-8-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.4%

8-amino quinoline (578-66-5) + phenyl chloroformate (1885-14-9) → quinolin-8-ylcarbamic acid phenyl ester (83848-82-2)

Guidance literature:

With pyridine; for 72h; Ambient temperature;

Reference yield:

→ quinolin-8-ylcarbamic acid phenyl ester (83848-82-2)

Guidance literature:

Reference yield: 91.0%

N-ethyl-cyclohexanamine (5459-93-8) + quinolin-8-ylcarbamic acid phenyl ester (83848-82-2) → 1-cyclohexyl-1-ethyl-3-(quinolin-8-yl)urea

Guidance literature:

In dimethyl sulfoxide; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.8b07708

upstream raw materials:

8-amino quinoline

phenyl chloroformate

Downstream raw materials:

1,2-dihydro-4H-imidazo<5,4,1-ij>quinolin-2-one

2-chloro-4H-imidazo<5,4,1-ij>quinoline

3-Chloro-benzoic acid 6-hydroxy-2-oxo-1,2,5,6-tetrahydro-4H-imidazo[4,5,1-ij]quinolin-5-yl ester

3-Chloro-benzoic acid 5-hydroxy-2-oxo-1,2,5,6-tetrahydro-4H-imidazo[4,5,1-ij]quinolin-6-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 83848-82-2 Phenyl-N-(8-Quinolyl)carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send