N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Base Information

Chemical Name:N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide
CAS No.:1071464-51-1
Molecular Formula:C₁₉H₁₅Cl₂N₃O₄
Molecular Weight:420.252
Hs Code.:

Synonyms:N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Suppliers and Price of N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

There total 7 articles about N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13831-30-6
acetoxyacetic acid

: 1071463-83-6
3-(3,4-dichlorobenzyl)-6-aminoquinazoline-4-(3H)-one

: 1071464-51-1
N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Guidance literature:: acetoxyacetic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 1h;

3-(3,4-dichlorobenzyl)-6-aminoquinazoline-4-(3H)-one; In dichloromethane; at 70 ℃; for 3h;

Reference yield:

: 1071463-83-6
3-(3,4-dichlorobenzyl)-6-aminoquinazoline-4-(3H)-one

: 13831-31-7
Acetoxyacetyl chloride

: 1071464-51-1
N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2009.04.004

Reference yield:

: 247569-82-0
2-amino-N-(3,4-dichlorobenzyl)-5-nitrobenzamide

: 1071464-51-1
N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-acetoxyacetamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: (1S)-10-camphorsulfonic acid / 0.5 h / 180 °C / Irradiation

2.1: hydrazine / nickel / methanol / 0.17 h / 50 °C

3.1: 1,1'-carbonyldiimidazole / dichloromethane / 1 h / 20 °C

3.2: 3 h / 70 °C

With (1S)-10-camphorsulfonic acid; 1,1'-carbonyldiimidazole; hydrazine; nickel; In methanol; dichloromethane;