3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid

Base Information

Chemical Name:3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid
CAS No.:39773-44-9
Molecular Formula:C₁₆H₁₄ClNO₃
Molecular Weight:303.745
Hs Code.:
European Community (EC) Number:651-167-7

Synonyms:CBMicro_008569;Cambridge id 5938825;Oprea1_454498;SCHEMBL7822835;SMSF0010184;AKOS024279329;CB11197;BIM-0008386.P001;3-benzoylamino-3-(4-chloro-phenyl)-propionic acid

Suppliers and Price of 3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:303.0662210
Heavy Atom Count:21
Complexity:361

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NC(CC(=O)O)C2=CC=C(C=C2)Cl

Technology Process of 3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid

There total 6 articles about 3-Benzoylamino-3-(4-chloro-phenyl)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 19947-39-8,131690-61-4
3-amino-3-(4-chlorophenyl)propionic acid

: 98-88-4
benzoyl chloride

: 39773-44-9
3-benzamido-3-(4-chlorophenyl)propanoic acid

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 0.005h; Cooling with ice;
DOI:10.1002/chem.201402380

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 39773-44-9
3-benzamido-3-(4-chlorophenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NH₄OAc / ethanol / 8 h / Heating

2: 49 percent / aq. NaOH / 0.5 h / 20 °C

With sodium hydroxide; ammonium acetate; In ethanol;
DOI:10.1002/anie.200502003

Reference yield:

: 1081776-84-2
methyl 3-benzamido-3-(4-chlorophenyl)propanoate

: 39773-44-9
3-benzamido-3-(4-chlorophenyl)propanoic acid

Guidance literature:: methyl 3-benzamido-3-(4-chlorophenyl)propanoate; With sodium hydroxide; In acetone; at 0 ℃; for 2h;

With hydrogenchloride; In water; pH=2;
DOI:10.1021/jm901407s