(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

Base Information

Chemical Name:(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester
CAS No.:85657-61-0
Molecular Formula:C₁₇H₁₉NO₇
Molecular Weight:349.34
Hs Code.:

Synonyms:(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

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Technology Process of (Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

There total 3 articles about (Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-19-7,77671-22-8
acetic acid

: 57943-84-7
Benzyl Clavulanate

: 85657-61-0
(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

Guidance literature:: With acetic acid; triethylamine; Yield given. Multistep reaction; 1) CH₂Cl₂, room temp., 20 min, 2) 2 h, room temp.;
DOI:10.1016/S0040-4039(00)85580-X

Reference yield:

: 63612-98-6
benzyl 9-O-methylclavulanate

: 64-19-7,77671-22-8
acetic acid

: 71742-68-2
Benzyl 3-hydroxypyrrole-3-carboxylate

: 85657-61-0
(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

: (Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3-hydroxy-5-methoxy-pent-2-enoic acid benzyl ester

Guidance literature:: With acetic acid; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1) CH₂Cl₂, room temp., 20 min, 2) 2 d, room temp.;
DOI:10.1016/S0040-4039(00)85580-X

Reference yield:

: 64-19-7,77671-22-8
acetic acid

: 57943-84-7
Benzyl Clavulanate

: 71742-68-2
Benzyl 3-hydroxypyrrole-3-carboxylate

: 85657-64-3
Carbonic acid benzyl ester 3-(3-hydroxy-1H-pyrrol-2-yl)-3-oxo-propyl ester

: 85657-61-0
(Z)-2-(2-Acetoxy-4-oxo-azetidin-1-yl)-3,5-dihydroxy-pent-2-enoic acid benzyl ester

Guidance literature:: With acetic acid; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1) CH₂Cl₂, room temp., 20 min, 2) 2 d, room temp.;
DOI:10.1016/S0040-4039(00)85580-X