1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Base Information

Chemical Name:1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene
CAS No.:318261-92-6
Molecular Formula:C₃₀H₃₈O₈
Molecular Weight:526.627
Hs Code.:

Synonyms:1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Suppliers and Price of 1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

There total 10 articles about 1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 318262-38-3
[3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-phenylethynyl]-trimethyl-silane

: 318261-92-6
1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Guidance literature:: With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; at 20 ℃; for 0.00833333h;
DOI:10.1021/ja002129e

Reference yield:

: 318261-40-4
(3,5-dibromo-phenyl)-pyrrolidin-1-yl-diazene

: 318261-92-6
1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Guidance literature:: Multi-step reaction with 6 steps

1.1: n-BuLi; B(OMe)3 / diethyl ether / 2 h

1.2: CH₃CO₃H / diethyl ether / 1 h / 0 °C

2.1: DEAD; PPh₃ / tetrahydrofuran

3.1: 80 percent / CuI; PPh₃; NEt₃ / Pd₂(dba)3 / 18 h / 80 °C

4.1: 76 percent / CH₃I / 12 h / 110 °C

5.1: 79 percent / CuI; PPh₃; NEt₃ / Pd₂(dba)3 / 70 °C

6.1: TBAF; H₂O / tetrahydrofuran / 0.01 h / 20 °C

With copper(l) iodide; n-butyllithium; Trimethyl borate; tetrabutyl ammonium fluoride; water; triethylamine; triphenylphosphine; diethylazodicarboxylate; methyl iodide; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; diethyl ether; 2.1: Mitsunobu coupling / 3.1: Sonogashira coupling;
DOI:10.1021/ja002129e

Reference yield:

: 318261-63-1
1-bromo-3-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzene

: 318261-92-6
1-Ethynyl-3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-5-(3-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylethynyl)-benzene

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / CuI; PPh₃; NEt₃ / Pd₂(dba)3 / 18 h / 80 °C

2: TBAF; H₂O / tetrahydrofuran / 0.01 h / 20 °C

3: 79 percent / CuI; PPh₃; NEt₃ / Pd₂(dba)3 / 70 °C

4: TBAF; H₂O / tetrahydrofuran / 0.01 h / 20 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; water; triethylamine; triphenylphosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; 1: Sonogashira coupling;
DOI:10.1021/ja002129e