3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester

Base Information

• Chemical Name: 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester
• CAS No.: 203571-34-0
• Molecular Formula: C₃₀H₂₈O₅
• Molecular Weight: 468.549
• Mol file: 203571-34-0.mol

Synonyms:3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester

Chemical Property of 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester

There total 1 articles about 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) + Caesium; 3-(3,4-bis-benzyloxy-phenyl)-2-hydroxy-propionate → 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester (203571-34-0)

Guidance literature:

In N,N-dimethyl-formamide; for 24h; Yield given; Ambient temperature;

DOI:10.1007/BF00806966

Reference yield: 97.0%

diethyl (2-chloro-2-oxoethyl)phosphonate (34170-81-5) + 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester (203571-34-0) → 3-(3,4-Bis-benzyloxy-phenyl)-2-[2-(diethoxy-phosphoryl)-acetoxy]-propionic acid benzyl ester (203571-36-2)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 15h; Ambient temperature;

DOI:10.1007/BF00806966

Reference yield: 95.0%

3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid benzyl ester (203571-34-0) + 3,4-dibenzyloxycinnamoyl chloride (203571-41-9) → (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 1-benzyloxycarbonyl-2-(3,4-bis-benzyloxy-phenyl)-ethyl ester (203571-43-1)

Guidance literature:

With dmap; In dichloromethane; for 0.5h;

DOI:10.1007/BF00806966

upstream raw materials:

benzyl bromide

Downstream raw materials:

3-(3,4-Bis-benzyloxy-phenyl)-2-[2-(diethoxy-phosphoryl)-acetoxy]-propionic acid benzyl ester

(E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 1-benzyloxycarbonyl-2-(3,4-bis-benzyloxy-phenyl)-ethyl ester