3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Base Information

Chemical Name:3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid
CAS No.:95384-22-8
Molecular Formula:C₂₂H₂₄N₂O₅S
Molecular Weight:428.509
Hs Code.:

Synonyms:3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Suppliers and Price of 3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

There total 6 articles about 3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 1-ethoxycarbonyl-methyl-3-[1-ethoxycarbonyl-2-benzylthio-(1R)-ethylamino]-2,3,4,5-tetrahydro-1H-[1]-benzazepin-2-one

: (R)-3-Benzylsulfanyl-2-((R)-1-carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-propionic acid

: 95384-22-8
3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Guidance literature:: With sodium hydroxide; In methanol; for 16h; Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/jm00149a010

Reference yield:

: 1-ethoxycarbonyl-methyl-3-[1-ethoxycarbonyl-2-benzylthio-(1R)-ethylamino]-2,3,4,5-tetrahydro-1H-[1]-benzazepin-2-one

: 95384-22-8
3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Guidance literature:: With sodium hydroxide; In methanol; ethyl acetate;

Reference yield:

: 953-18-4
S-benzyl-L-cysteine ethyl ester

: 95384-22-8
3(S)-<<(1R)-2-(benzylthio)-1-carboxyethyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: di-n-butyltin dichloride / CHCl₃ / 16 h / Heating

2: 41 percent / acetic acid, NaBH₃CN / methanol / 16 h / Ambient temperature

3: 27 percent / 2N aq. NaOH / methanol / 16 h / Ambient temperature

With sodium hydroxide; dibutyltin chloride; sodium cyanoborohydride; acetic acid; In methanol; chloroform;
DOI:10.1021/jm00149a010