953-18-4Relevant articles and documents
Synthesis of methyl 2-(1',1'-demethyl-2'-oxopropyl)thiazole-4-carboxylate and related 2,4-disubstituted thiazoles. Key intermediates in the synthesis of anthelmintic agents based on marine natural product
Serra, Gloria,Mahler, Graciela,Manta, Eduardo
, p. 2035 - 2048 (2007/10/03)
Two methodologies, cyclodehydration of amides with TiCl4 and cyclodehydration of β-hydroxy thioamides with PEG linked Burgess reagent were used in order to obtain 2,4-disubstituted thiazole rings (2) and (3) respectively. The scope and limitati