[3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

Base Information

• Chemical Name: [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine
• CAS No.: 163561-70-4
• Molecular Formula: C₃₁H₃₅ClN₂O₃S
• Molecular Weight: 551.149

Synonyms:[3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

Chemical Property of [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

There total 2 articles about [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-(3-bromopropoxy)-3-chlorobenzene (37142-46-4) + Propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine (851727-83-8) → [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine (163561-70-4)

Guidance literature:

With sodium carbonate; In acetonitrile; for 72h; Heating;

DOI:10.1021/jm00012a022

Reference yield:

3-(p-toluenesulfonyl)-6,7,8,9-tetrahydro-3H-benzindol-8-one (155591-01-8) → [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine (163561-70-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) p-toluenesulfonic acid, 2.) NaCNBH₃ / 1.) toluene, reflux, overnight, 2.) THF, CH₃OH, RT, overnight

2: 89 percent / Na₂CO₃ / acetonitrile / 72 h / Heating

With sodium cyanoborohydride; sodium carbonate; toluene-4-sulfonic acid; In acetonitrile;

DOI:10.1021/jm00012a022

Reference yield: 86.0%

[3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine (163561-70-4) → N-[3-(m-chlorophenoxy)propyl]-N-propyl-N-(6,7,8,9-tetrahydro-3H-benz[e]indol-8-yl)amine (163561-69-1)

Guidance literature:

With sodium methylate; In tetrahydrofuran; methanol; Heating;

DOI:10.1021/jm00012a022

upstream raw materials:

1-(3-bromopropoxy)-3-chlorobenzene

Propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

3-(p-toluenesulfonyl)-6,7,8,9-tetrahydro-3H-benzindol-8-one

Downstream raw materials:

N-[3-(m-chlorophenoxy)propyl]-N-propyl-N-(6,7,8,9-tetrahydro-3H-benz[e]indol-8-yl)amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 163561-70-4 [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send