155591-01-8

Upstream product

• 74-85-1 ethene 
• 155591-00-7 1-(p-toluenesulfonyl)indol-4-acetic acid 
• 92573-18-7 ethyl 1-{[(4-methylphenyl)sulfonyl]-1H-indol-4-yl}acetate 
• 1027843-58-8 [1-(Toluene-4-sulfonyl)-1H-indol-4-yl]-acetyl chloride 

Downstream Products

• 1026631-75-3 8-Azepan-1-yl-3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indole 
• 163561-73-7 4,4-Dimethyl-1-(4-{propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amino}-butyl)-piperidine-2,6-dione 
• 163561-97-5 (3-Phenyl-propyl)-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine 
• 163561-69-1 N-[3-(m-chlorophenoxy)propyl]-N-propyl-N-(6,7,8,9-tetrahydro-3H-benz[e]indol-8-yl)amine 
• 163561-66-8 N-[3-(o-methoxyphenyl)propyl]-N-propyl-N-(6,7,8,9-tetrahydro-3H-benz[e]indol-8-yl)amine 
• 136925-15-0 6,7,8,9-tetrahydro-N-benzyl-N-n-propyl-8-amino-3H-benz[e]indole 
• 163561-98-6 (3-Phenyl-propyl)-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine 
• 1026297-95-9 3-(2-Methoxy-phenyl)-N-propyl-N-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-propionamide 
• 163561-70-4 [3-(3-Chloro-phenoxy)-propyl]-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine 
• 163562-16-1 Phenethyl-propyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine 
• 1027263-21-3 (3-Phenyl-propyl)-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl]-amine 
• 1028260-83-4 Dipropyl-[3-(toluene-4-sulfonyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl]-amine 
• 163561-64-6 N-(2-phenylethyl)-N-propyl-N-(6,7,8,9-tetrahydro-3H-benz[e]indol-8-yl)amine 
• 163562-10-5 3-N-(tolylsulfonyl)-6,7,8,9-tetrahydro-3H-benzindole-8-carbaldehyde 

Relevant academic research and scientific papers

Sulfonyltetrahydro-3H-benzo(E)indole-8-amine compounds as 5-Hydroxytryptamine-6 ligands

The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of a CNS disorder related to or affected by the 5-HT6 receptor.

Synthesis of (R)- and (S)-1-formyl-6,7,8,9-tetrahydro-N,N-(dipropyl)-3H- benz[e]indol-8-amines: Potent and orally active 5-HT(1A) receptor agonists

An efficient synthesis of the potent and orally active 5-HT(1A) agonists, (R)-(+)- and (S)-(-)-l-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H- benz[e]indol-8-amines 1a and 1b, is described. This synthesis was accomplished in twelve steps from commercially av