butyl-malonic acid-dianilide

Base Information

• Chemical Name: butyl-malonic acid-dianilide
• CAS No.: 26971-94-8
• Molecular Formula: C₁₉H₂₂N₂O₂
• Molecular Weight: 310.396
• Mol file: 26971-94-8.mol

Synonyms:butyl-malonic acid-dianilide

Chemical Property of butyl-malonic acid-dianilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of butyl-malonic acid-dianilide

There total 3 articles about butyl-malonic acid-dianilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

aniline (62-53-3) + diethyl butylmalonate (133-08-4) → butyl-malonic acid-dianilide (26971-94-8)

Guidance literature:

at 160 ℃; for 5h;

DOI:10.1021/jm00385a031

Reference yield:

1-bromo-butane (109-65-9) + N,N'-diphenylmalonamide (621-10-3) → butyl-malonic acid-dianilide (26971-94-8)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; N,N-dimethyl-formamide; at 80 ℃; for 8h; Inert atmosphere;

DOI:10.1021/jacs.1c00503

Reference yield:

→ butyl-malonic acid-dianilide (26971-94-8)

Guidance literature:

Anilin, Etyl-n-butylmalonat;

upstream raw materials:

aniline

diethyl butylmalonate

1-bromo-butane

N,N'-diphenylmalonamide

Downstream raw materials:

4-butyl-1,2-diphenylpyrazolidine

Refernces

• 1、 Ishimaru, Keiko,Kuriyama, Masami,Minato, Daishirou,Mizuta, Satoshi,Onomura, Osamu,Yamamoto, Kosuke. "Diastereodivergent Synthesis of Bromoiminolactones: Electrochemical and Chemical Bromoiminolactonization of α-Allylmalonamides". supporting information. p. 1204 - 1208. Retrieved 2019/06/08.