N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Base Information

Chemical Name:N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium
CAS No.:1360461-69-3
Molecular Formula:C₄₉H₈₃NO₆
Molecular Weight:782.201
Hs Code.:

Synonyms:N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Suppliers and Price of N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description DOBAQ, N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium, is a cationic lipids with a quaternary amine and unsaturated hydrocarbon chains. DOBAQ also serves as a pH-sensitive transfection reagent.

Technology Process of N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

There total 4 articles about N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1378942-38-1
C₅₃H₉₂NO₆⁽¹⁺⁾

: 1360461-69-3
N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Guidance literature:: With trifluoroacetic acid; In dichloromethane; TIPS; at 20 ℃; for 1h;
DOI:10.1039/c2cc31710a

Reference yield:

: 108052-76-2
4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester

: 1360461-69-3
N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / tetrahydrofuran; methanol / 16 h / 35 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 16 h / 20 °C

3: 16 h / 0 - 20 °C

4: trifluoroacetic acid / TIPS; dichloromethane / 1 h / 20 °C

With dmap; potassium carbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; TIPS;
DOI:10.1039/c2cc31710a

Reference yield:

: 1378942-34-7
C₁₆H₂₅NO₄

: 1360461-69-3
N-(4-carboxybenzyl)-N,N-dimethyl-2,3-bis(oleoyloxy)propan-1-aminium

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 16 h / 20 °C

2: 16 h / 0 - 20 °C

3: trifluoroacetic acid / TIPS; dichloromethane / 1 h / 20 °C

With dmap; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane; TIPS;
DOI:10.1039/c2cc31710a