<2R-<2α(1R,2R)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Base Information

Chemical Name:<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester
CAS No.:96614-75-4
Molecular Formula:C₃₂H₄₂O₉
Molecular Weight:570.68
Hs Code.:

<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Synonyms:<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Suppliers and Price of <2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

There total 7 articles about <2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.8%

: 40786-69-4
1-(2,4-dihydroxy-3-propylphenyl)ethanone

: 96614-74-3
<2R-<2α(1R*,2R*)>>-6-acetyl-7-<(5-bromopentyl)oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

: 96614-75-4
<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; acetone; for 2h; Heating;
DOI:10.1021/jm00128a028

Reference yield:

: 23866-72-0
ethyl 7-hydroxy-4-oxo-4H-chromen-2-carboxylate

: 96614-75-4
<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 73.4 percent / H₂ / 10percent Pd/C / acetic acid / 41 h / Ambient temperature

2: 79 percent / pyridine / 24 h / Ambient temperature

3: 1.) BF₃*Et₂O, AcOH, Ac₂O, 2.) p-TsOH*H₂O / 1.) reflux, 18.5 h, 2.) reflux, 20 h

4: 100 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 4 h / Ambient temperature

5: 1.) N,N'-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine, 2.) K₂CO₃ / 1.) CH₂Cl₂, room temperature, 4 h, 2.) acetone, DMF, reflux, 18 h

6: 50.8 percent / K₂CO₃ / acetone; dimethylformamide / 2 h / Heating

With pyridine; dmap; lithium hydroxide; boron trifluoride diethyl etherate; hydrogen; acetic anhydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; water; acetic acid; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm00128a028

Reference yield:

: 96566-14-2
(R)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-carboxylic acid,ethyl ester

: 96614-75-4
<2R-<2α(1R*,2R*)>>-6-acetyl-7-<<5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl>oxy>-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 2-hydroxy-1-methylpropyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / pyridine / 24 h / Ambient temperature

2: 1.) BF₃*Et₂O, AcOH, Ac₂O, 2.) p-TsOH*H₂O / 1.) reflux, 18.5 h, 2.) reflux, 20 h

3: 100 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 4 h / Ambient temperature

4: 1.) N,N'-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine, 2.) K₂CO₃ / 1.) CH₂Cl₂, room temperature, 4 h, 2.) acetone, DMF, reflux, 18 h

5: 50.8 percent / K₂CO₃ / acetone; dimethylformamide / 2 h / Heating

With pyridine; dmap; lithium hydroxide; boron trifluoride diethyl etherate; acetic anhydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm00128a028