(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Base Information

Chemical Name:(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate
CAS No.:1454797-29-5
Molecular Formula:C₄₈H₅₀O₁₀S₂
Molecular Weight:851.051
Hs Code.:

Synonyms:(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Suppliers and Price of (2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

There total 4 articles about (2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1454797-27-3
(2R,3S,4R,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diol

: 124-63-0
methanesulfonyl chloride

: 1454797-29-5
(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jo401613v

Reference yield:

: (4S,5S,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-(trityloxymethyl)tetrahydro-2H-pyran-2,3-diol

: 1454797-29-5
(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium periodate / water; acetonitrile / 5 h / 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 1.25 h / 0 °C / Inert atmosphere

3: triethylamine; dmap / dichloromethane / 1 h / 0 °C / Inert atmosphere

With dmap; sodium tetrahydroborate; sodium periodate; triethylamine; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/jo401613v

Reference yield:

: 1454797-10-4
(2R,3S,4S)-1,3,4-tris(benzyloxy)-5-oxo-6-(trityloxy)hexan-2-yl formate

: 1454797-29-5
(2R,3R,4S,5R)-1,3,4-tris(benzyloxy)-6-(trityloxy)hexane-2,5-diyldimethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 1.25 h / 0 °C / Inert atmosphere

2: triethylamine; dmap / dichloromethane / 1 h / 0 °C / Inert atmosphere

With dmap; sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;
DOI:10.1021/jo401613v