C₂₀H₂₄O₅

Base Information

• Chemical Name: C₂₀H₂₄O₅
• CAS No.: 106569-72-6
• Molecular Formula: C₂₀H₂₄O₅
• Molecular Weight: 344.408
• Mol file: 106569-72-6.mol

Synonyms:C₂₀H₂₄O₅

Chemical Property of C₂₀H₂₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₄O₅

There total 35 articles about C₂₀H₂₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-octynolic acid (76469-08-4) → C20H24O5 (106569-72-6)

Guidance literature:

Multi-step reaction with 15 steps

1: (COCl)2

2: 1) nBuLi / 1) THF

3: 1) (Me₂Si)2NLi / 1) THF, -78 deg C, 2) THF, -78 to 0 deg C

4: LiAlH₄ / tetrahydrofuran

5: KH / tetrahydrofuran

6: 1) ozone

7: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

8: Me₂AlCl / CH₂Cl₂

10: ozone

11: 1) t-BuLi / 1) THF, 2) THF, HMPA

12: H₃O⁽¹⁺⁾

13: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

14: ZnBr₂ / CH₂Cl₂

15: CSA / benzene

With quinoline; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; (Me₂Si)2NLi; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; benzene;

DOI:10.1021/ja00238a060

Reference yield:

benzyl bromide (100-39-0) → C20H24O5 (106569-72-6)

Guidance literature:

Multi-step reaction with 11 steps

1: KH / tetrahydrofuran

2: 1) ozone

3: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

4: Me₂AlCl / CH₂Cl₂

6: ozone

7: 1) t-BuLi / 1) THF, 2) THF, HMPA

8: H₃O⁽¹⁺⁾

9: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

10: ZnBr₂ / CH₂Cl₂

11: CSA / benzene

With quinoline; oxalyl dichloride; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; benzene;

DOI:10.1021/ja00238a060

Reference yield:

5-octynoyl chloride (106569-63-5) → C20H24O5 (106569-72-6)

Guidance literature:

Multi-step reaction with 14 steps

1: 1) nBuLi / 1) THF

2: 1) (Me₂Si)2NLi / 1) THF, -78 deg C, 2) THF, -78 to 0 deg C

3: LiAlH₄ / tetrahydrofuran

4: KH / tetrahydrofuran

5: 1) ozone

6: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

7: Me₂AlCl / CH₂Cl₂

9: ozone

10: 1) t-BuLi / 1) THF, 2) THF, HMPA

11: H₃O⁽¹⁺⁾

12: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

13: ZnBr₂ / CH₂Cl₂

14: CSA / benzene

With quinoline; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; (Me₂Si)2NLi; camphor-10-sulfonic acid; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; zinc dibromide; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane; benzene;

DOI:10.1021/ja00238a060

upstream raw materials:

Tetrahydro-4H-pyran-4-one

1,5-dichloropentan-3-one

3,3-Dimethyl-1,5,9-trioxa-spiro[5.5]undecane

7-Bromo-3,3-dimethyl-1,5,9-trioxa-spiro[5.5]undecane

Downstream raw materials:

C₂₄H₃₄O₅Si

C₂₄H₃₄O₅Si

(+)-Phyllanthocin

(+)-phyllanthocindiol methyl ester