Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide (1:1), (5a,6a)-

Base Information

• Chemical Name: Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide (1:1), (5a,6a)-
• CAS No.: 14054-17-2
• Molecular Formula: C18H22 N O3 . I
• Molecular Weight: 427.282
• Mol file: 14054-17-2.mol

Synonyms:Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide, (5a,6a)- (9CI); Morphine methiodide (6CI); Morphine methyliodide; N-Methylmorphine iodide

Chemical Property of Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide (1:1), (5a,6a)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide (1:1), (5a,6a)-

There total 3 articles about Morphinanium,7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethyl-, iodide (1:1), (5a,6a)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

MORPHIN (57-27-2) + methyl iodide (74-88-4) → morphine methiodide (14054-17-2)

Guidance literature:

In acetonitrile; at 20 ℃;

Reference yield:

→ (5α,6α)-7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-dimethylmorphinanium iodide (14054-17-2)

Guidance literature:

Morphin, Methyliodid;

DOI:10.1111/j.2042-7158.1978.tb13196.x

Reference yield:

morphine (143-70-4) + methyl iodide (74-88-4) → 4,5α-epoxy-3,6β-dihydroxy-17,17-dimethyl-morphin-7-enium; iodide (14054-17-2)

Guidance literature:

With methanol;

upstream raw materials:

MORPHIN

methyl iodide

morphine

Refernces

• 1、 -. "USE OF OPIOID COMPOUNDS IN PERIPHERAL PAIN, WOUND HEALING AND SCAR FORMATION". Page/Page column 8. . Retrieved 2009/12/23.
• 2、 Iorio,Disciullo,Mazzeo Farina,Frigeni. "Diastereoisomeric quaternary morphinium salts: Synthesis, stereochemistry and analgesic properties". . p. 11 - 16. Retrieved 2007/10/02.