Tert-butyl Aziridine-2-carboxylate

Base Information

Chemical Name:Tert-butyl Aziridine-2-carboxylate
CAS No.:82912-42-3
Molecular Formula:C7H13 N O2
Molecular Weight:143.18
Hs Code.:2933990090
European Community (EC) Number:841-366-9
DSSTox Substance ID:DTXSID40467158
Nikkaji Number:J2.424.910G
Mol file:82912-42-3.mol

Synonyms:Tert-butyl Aziridine-2-carboxylate;82912-42-3;DTXSID40467158;AKOS006353805;Aziridine-2-carboxylic acid tert-butyl ester;EN300-7352749;F2147-2414

Suppliers and Price of Tert-butyl Aziridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Tert-butyl Aziridine-2-carboxylate

Chemical Property:

Boiling Point:66 °C(Press: 12 Torr)
PKA:5.76±0.40(Predicted)
PSA：48.24000
Density:1.049±0.06 g/cm3(Predicted)
LogP:0.62870
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:143.094628657
Heavy Atom Count:10
Complexity:148

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C1CN1

Technology Process of Tert-butyl Aziridine-2-carboxylate

There total 4 articles about Tert-butyl Aziridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 82912-42-3
(+/-)-aziridine-2-carboxylic acid tert-butyl ester

Guidance literature:: With 4-methyl-morpholine; sodium hydroxide; O-(diphenylphosphinyl)hydroxylamine; In acetonitrile; at 20 ℃; for 10h;
DOI:10.1021/ol062852v

Reference yield: 76.0%

: 138034-79-4,49855-41-6
tert-butyl 2,3-dibromopropionate

: 82912-42-3
(+/-)-aziridine-2-carboxylic acid tert-butyl ester

Guidance literature:: With ammonia; for 2h;
DOI:10.1016/S0040-4020(01)87968-0

Reference yield: 60.0%

: 5950-34-5,118396-26-2,151526-74-8,151526-75-9
methyl aziridine-2-carboxylate

: 75-65-0
tert-butyl alcohol

: 82912-42-3
(+/-)-aziridine-2-carboxylic acid tert-butyl ester

Guidance literature:: tert-butyl alcohol; With n-butyllithium; In tetrahydrofuran; hexane; at -20 ℃; for 0.25h; Inert atmosphere;

methyl aziridine-2-carboxylate; In tetrahydrofuran; hexane; at -20 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2013.11.052