Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Base Information

Chemical Name:Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester
CAS No.:154959-89-4
Molecular Formula:C₂₄H₂₃NO₆S₂
Molecular Weight:485.582
Hs Code.:

Synonyms:Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Suppliers and Price of Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

There total 5 articles about Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.9%

: 98-59-9
p-toluenesulfonyl chloride

: 154959-88-3
1-(2-Benzolsulfonylmethyl-phenyl)-4-hydroxymethyl-2-azetidinon

: 154959-89-4
Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Guidance literature:: With dmap; In dichloromethane; for 24h; Heating;
DOI:10.1007/BF00811676

Reference yield:

: 95539-67-6
2-[(phenylsulfonyl)methyl]aniline

: 154959-89-4
Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Guidance literature:: Multi-step reaction with 5 steps

1: benzene / Heating

2: 70 percent / Et₃N / benzene / 1.) 80 deg C, 1-2 h, 2.) 80 deg C to r.t., 3 h

3: 74.9 percent / Bu3SnH, α,α'-azoisobutyronitrile / benzene / Heating

4: 1.) O₃, 2.) NaBH₄ / 1.) MeOH, CH₂Cl₂, -55 deg C, 30 min, 2.) MeOH_. CH₂Cl₂, -30 deg C

5: 82.9 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 24 h / Heating

With dmap; sodium tetrahydroborate; azobisisobutyronitrile; tri-n-butyl-tin hydride; ozone; triethylamine; In dichloromethane; benzene;
DOI:10.1007/BF00811676

Reference yield:

: N-(2-Phenylsulfonylmethylphenyl)-zimtaldehydimin

: 154959-89-4
Toluolsulfonsaeure 1-(2-benzolsulfonylmethyl-phenyl)-4-oxoazetidin-2-ylmethylester

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / Et₃N / benzene / 1.) 80 deg C, 1-2 h, 2.) 80 deg C to r.t., 3 h

2: 74.9 percent / Bu3SnH, α,α'-azoisobutyronitrile / benzene / Heating

3: 1.) O₃, 2.) NaBH₄ / 1.) MeOH, CH₂Cl₂, -55 deg C, 30 min, 2.) MeOH_. CH₂Cl₂, -30 deg C

4: 82.9 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 24 h / Heating

With dmap; sodium tetrahydroborate; azobisisobutyronitrile; tri-n-butyl-tin hydride; ozone; triethylamine; In dichloromethane; benzene;
DOI:10.1007/BF00811676