rac 7-Hydroxy Propranolol

Base Information

Chemical Name:rac 7-Hydroxy Propranolol
CAS No.:81907-81-5
Molecular Formula:C₁₆H₂₁NO₃
Molecular Weight:275.348
Hs Code.:
DSSTox Substance ID:DTXSID50433884
Nikkaji Number:J396.650J
ChEMBL ID:CHEMBL105817
Mol file:81907-81-5.mol

Synonyms:rac 7-Hydroxy Propranolol;81907-81-5;8-[2-hydroxy-3-(propan-2-ylamino)propoxy]naphthalen-2-ol;7-Hydroxypropranolol;2-Naphthalenol,8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-;CHEMBL105817;DTXSID50433884;8-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-2-naphthalenol;(+/-)-8-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-2-naphthalenol;AKOS030254499;PD060439;FT-0670057;8-{2-Hydroxy-3-[(propan-2-yl)amino]propoxy}naphthalen-2-ol

Suppliers and Price of rac 7-Hydroxy Propranolol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
rac 7-Hydroxy Propranolol
1mg
$ 446.00

TRC
rac7-HydroxyPropranolol
1mg
$ 175.00

American Custom Chemicals Corporation
RAC 7-HYDROXY PROPRANOLOL 95.00%
10MG
$ 1871.10

American Custom Chemicals Corporation
RAC 7-HYDROXY PROPRANOLOL 95.00%
1MG
$ 739.20

Total 4 raw suppliers

Chemical Property of rac 7-Hydroxy Propranolol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:132-134°C
Refractive Index:1.602
Boiling Point:487.526°C at 760 mmHg
Flash Point:248.647°C
PSA：61.72000
Density:1.169g/cm³
LogP:2.67400
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:275.15214353
Heavy Atom Count:20
Complexity:285

Purity/Quality:

99% ^*data from raw suppliers

rac 7-Hydroxy Propranolol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NCC(COC1=CC=CC2=C1C=C(C=C2)O)O

Technology Process of rac 7-Hydroxy Propranolol

There total 2 articles about rac 7-Hydroxy Propranolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76275-53-1
1-Isopropylamino-3-(7-methoxy-naphthalen-1-yloxy)-propan-2-ol

: 81907-81-5
7-Hydroxypropranolol

Guidance literature:: With pyridine hydrochloride; at 155 - 180 ℃; for 15h;
DOI:10.1021/jm00135a014

Reference yield:

: 67247-13-6
7-methoxynaphth-1-ol

: 81907-81-5
7-Hydroxypropranolol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Dowex-1 resin (OH form) / 1.) 90 min, 2.) 30 deg C, 67 h

2: pyridine hydrochloride / 15 h / 155 - 180 °C

With Dowex-1 resin (OH form); pyridine hydrochloride;
DOI:10.1021/jm00135a014