dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Base Information

Chemical Name:dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate
CAS No.:370859-43-1
Molecular Formula:C₄₀H₄₈F₃N₂O₁₉P
Molecular Weight:948.792
Hs Code.:

dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Synonyms:dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Suppliers and Price of dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

There total 5 articles about dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1623-08-1
phosphoric acid dibenzyl ester

: 370859-42-0
2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-2-trifluoromethyl-(2-acetamido-3,6-di-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-[2,1-d]-2-oxazoline

: 370859-43-1
dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Guidance literature:: In 1,2-dichloro-ethane; at 80 - 90 ℃; for 5h;
DOI:10.1021/jo0100345

Reference yield:

: 7531-49-9
2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,6-di-O-acetyl-2-deoxy-α-D-glucopyranosyl chloride

: 370859-43-1
dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / H₂O / acetone / Heating

2: 97 percent / pyridine / CH₂Cl₂ / 2 h / 0 °C

3: HBr / acetic acid; CH₂Cl₂ / 3 h / 20 °C

4: 197.7 mg / 2,6-lutidine / acetonitrile / 13 h / 20 °C

5: 64 percent / 1,2-dichloro-ethane / 5 h / 80 - 90 °C

With pyridine; 2,6-dimethylpyridine; water; hydrogen bromide; In dichloromethane; acetic acid; 1,2-dichloro-ethane; acetone; acetonitrile;
DOI:10.1021/jo0100345

Reference yield:

: Acetic acid (2R,3S,4R,5R)-2-acetoxymethyl-6-bromo-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yloxy)-5-(2,2,2-trifluoro-acetylamino)-tetrahydro-pyran-4-yl ester

: 370859-43-1
dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 197.7 mg / 2,6-lutidine / acetonitrile / 13 h / 20 °C

2: 64 percent / 1,2-dichloro-ethane / 5 h / 80 - 90 °C

With 2,6-dimethylpyridine; In 1,2-dichloro-ethane; acetonitrile;
DOI:10.1021/jo0100345