7531-49-9

Usage

Uses

Used in Organic Synthesis:
N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside is used as a key intermediate in organic synthesis for the development of new chemical compounds. Its unique structure allows for the creation of a wide range of derivatives with potential applications in various fields, such as pharmaceuticals, materials science, and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside is used as a building block for the synthesis of novel drug candidates. Its structural features can be exploited to design and develop new therapeutic agents with improved pharmacological properties, such as enhanced bioavailability, selectivity, and potency.
Used in Materials Science:
In materials science, N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside can be utilized as a component in the development of advanced materials with specific properties. Its ability to form complexes with other molecules can be harnessed to create materials with unique characteristics, such as improved mechanical strength, thermal stability, or biocompatibility.
Used in Agrochemical Industry:
N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside can also find applications in the agrochemical industry, where it can be used as a starting material for the synthesis of new pesticides, herbicides, or fertilizers. Its unique chemical properties may contribute to the development of more effective and environmentally friendly agrochemical products.

Upstream product

• 77224-08-9 2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-amino-2-deoxy-D-glucopyranose 
• 75-36-5 acetyl chloride 
• 7284-18-6 chitobiose octaacetate 

Downstream Products

• 370859-43-1 dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate 
• 117143-01-8 N⁴-<2-Acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-3,6-di-O-acetyl-2-desoxy-β-D-glucopyranosyl>-L-asparaginyl-L-phenylalanyl-L-treonin-allylester-trifluoracetat 
• 98304-21-3 N⁴-<2-Acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-3,6-di-O-acetyl-2-desoxy-β-D-glucopyranosyl>-N²-(tert-butyloxycarbonyl)-L-asparaginyl-L-phenylalanyl-L-threonin-allylester 
• 98304-20-2 N⁴-<2-Acetamido-4-O-(2-acetamido-2-desoxy-β-D-glucopyranosyl)-2-desoxy-β-D-glucopyranosyl>-N²-(tert-butyloxycarbonyl)-L-asparaginyl-L-phenylalanyl-L-treoninamid 

Relevant academic research and scientific papers

NOVEL ANTI-INFLAMMATORY PRO-DRUGS

The present invention relates to compounds according to formula (I): wherein R is selected from the group consisting of anti-inflammatory agents and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising compounds of formula (I) and the use of these pharmaceutical compositions for the treatment or prophylaxis of chronic inflammatory diseases, in particular those that are caused by chronically activated macrophages. The chronic inflammatory disease is in particular atherosclerosis, (rheumatoid) arthritis, an (auto)immune disease or sarcoidosis.

The (2-Phenyl-2-trimethylsilyl)ethyl-(PTMSEL)-Linker in the Synthesis of Glycopeptide Partial Structures of Complex Cell Surface Glycoproteins

The (2-phenyl-2-trimethylsilyl)ethyl-(PTMSEL) linker represents a novel fluoride-sensitive anchor for the solid-phase synthesis of protected peptides and glycopeptides. Its cleavage is achieved under almost neutral conditions using tetrabutylammonium fluo

Probing the mechanism of a fungal glycosyltransferase essential for cell wall biosynthesis. UDP-Chitobiose is not a substrate for chitin synthase

Chitin synthase is responsible for the biosynthesis of chitin, an essential component of the fungal cell wall. There is a long-standing question as to whether "processive" transferases such as chitin synthase operate in the same manner as non-processive transferases. The question arises from analysis of the polysaccharide structure - in chitin, for instance, each sugar residue is rotated ca. 180 deg relative to the preceding sugar in the chain. This requires that the enzyme account for the alternating "up/down" configuration during biosynthesis. An enzyme with a single active site, analogous to the non-processive transferases - would have to accommodate a distorted glycosidic linkage at every other synthetic step. An alternative proposal is that the enzyme might assemble the disaccharide donor, addressing the "up/down" conformational problem prior to polymer synthesis. We present compelling evidence that this latter hypothesis is incorrect.

Enzyme-Catalyzed Glycosylation of Peptides Using a Synthetic Lipid Disaccharide Substrate

A lipid disaccharide, consisting of chitobiose linked to dolichol via an α-1-pyrophosphate, has been synthesized for use as a substrate in the enzyme-catalyzed glycosylation of peptides.For the purpose of confirming the structure of the reaction product,

Synthesis of Partial Structures of N-Glycopeptides Representing the Linkage Regions of the Transmembrane Neuraminidase of an Influenca Virus and of Factor B of the Human Complement System

The synthesis of the protected N-chitobiosylasparaganine peptides 12a and 14, which correspond to the linkage regions of factor B of the human complement system and of the transmembrane neuraminidase of an influenza virus, was accomplished by applying the protecting group combination Boc group/allyl ester together with acetyl groups in the carbohydrate part.From 12a the allyl ester and the acetates were simultaneously removed using ammonia in methanol.The Boc group was cleaved without side reactions using anhydrous trifluoroacetic acid.Attempts to remove the Boc-protecting group from the glycopeptides already deblocked in the carbohydrate part resulted predominantly in the cleavage of the O-glycosidic bond.