7531-49-9

Basic information

• Product Name: N,N'-DIACETYL-3,6,3',4',6'-PENTA-O-ACETYL-1-CHLOROCHITOBIOSIDE
• Synonyms: N,N'-DIACETYL-3,6,3',4',6'-PENTA-O-ACETYL-1-CHLOROCHITOBIOSIDE;2-(AcetylaMino)-2-deoxy-4-O-[3,4,6-tri-O-acetyl-2-(acetylaMino)-2-deoxy-β-D-glucopyranosyl]-α-D-glucopyranosyl Chloride 3,6-Diacetate;2-AcetaMido-4-O-(2-acetaMido-2-deoxy-β-D-glucopyranosyl)-
• CAS NO: 7531-49-9
• Molecular Formula: C26H37ClN2O15
• Molecular Weight: 653.02938
• Product Categories: Carbohydrates & Derivatives;Chiral Reagents;Oligosaccharides
• Mol File: 7531-49-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Solubility: Chloroform
• CAS DataBase Reference: N,N'-DIACETYL-3,6,3',4',6'-PENTA-O-ACETYL-1-CHLOROCHITOBIOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIACETYL-3,6,3',4',6'-PENTA-O-ACETYL-1-CHLOROCHITOBIOSIDE(7531-49-9)
• EPA Substance Registry System: N,N'-DIACETYL-3,6,3',4',6'-PENTA-O-ACETYL-1-CHLOROCHITOBIOSIDE(7531-49-9)

Safety Data

• Hazardous Substances Data: 7531-49-9(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

N,N’-Diacetyl-3,6,3’,4’,6’-penta-O-acetyl-1-chlorochitobioside (cas# 7531-49-9) is a compound useful in organic synthesis.

Upstream product

• 77224-08-9 2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-amino-2-deoxy-D-glucopyranose 
• 75-36-5 acetyl chloride 
• 7284-18-6 chitobiose octaacetate 

Downstream Products

• 117143-01-8 N⁴-<2-Acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-3,6-di-O-acetyl-2-desoxy-β-D-glucopyranosyl>-L-asparaginyl-L-phenylalanyl-L-treonin-allylester-trifluoracetat 
• 98304-21-3 N⁴-<2-Acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-desoxy-β-D-glucopyranosyl)-3,6-di-O-acetyl-2-desoxy-β-D-glucopyranosyl>-N²-(tert-butyloxycarbonyl)-L-asparaginyl-L-phenylalanyl-L-threonin-allylester 
• 98304-20-2 N⁴-<2-Acetamido-4-O-(2-acetamido-2-desoxy-β-D-glucopyranosyl)-2-desoxy-β-D-glucopyranosyl>-N²-(tert-butyloxycarbonyl)-L-asparaginyl-L-phenylalanyl-L-treoninamid 
• 370859-43-1 dibenzyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-3,6-di-O-acetyl-2-deoxy-2-trifluoroacetamido-α-D-glucopyranosyl phosphate 

Relevant articles and documents

NOVEL ANTI-INFLAMMATORY PRO-DRUGS

The present invention relates to compounds according to formula (I): wherein R is selected from the group consisting of anti-inflammatory agents and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising compounds of formula (I) and the use of these pharmaceutical compositions for the treatment or prophylaxis of chronic inflammatory diseases, in particular those that are caused by chronically activated macrophages. The chronic inflammatory disease is in particular atherosclerosis, (rheumatoid) arthritis, an (auto)immune disease or sarcoidosis.

Probing the mechanism of a fungal glycosyltransferase essential for cell wall biosynthesis. UDP-Chitobiose is not a substrate for chitin synthase

Chitin synthase is responsible for the biosynthesis of chitin, an essential component of the fungal cell wall. There is a long-standing question as to whether "processive" transferases such as chitin synthase operate in the same manner as non-processive transferases. The question arises from analysis of the polysaccharide structure - in chitin, for instance, each sugar residue is rotated ca. 180 deg relative to the preceding sugar in the chain. This requires that the enzyme account for the alternating "up/down" configuration during biosynthesis. An enzyme with a single active site, analogous to the non-processive transferases - would have to accommodate a distorted glycosidic linkage at every other synthetic step. An alternative proposal is that the enzyme might assemble the disaccharide donor, addressing the "up/down" conformational problem prior to polymer synthesis. We present compelling evidence that this latter hypothesis is incorrect.

Kombinierte chemoenzymatische Synthese von N-Glycoproteinbausteinen

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