(+)-(S)-Mexiletine hydrochloride

Base Information

Chemical Name:(+)-(S)-Mexiletine hydrochloride
CAS No.:81771-85-9
Molecular Formula:C11H17 N O . Cl H
Molecular Weight:215.723
Hs Code.:
Mol file:81771-85-9.mol

Synonyms:2-Propanamine,1-(2,6-dimethylphenoxy)-, hydrochloride, (2S)- (9CI); 2-Propanamine, 1-(2,6-dimethylphenoxy)-,hydrochloride, (S)-; (+)-(S)-Mexiletine hydrochloride; (+)-Mexiletinehydrochloride; [(S)-2-[(2,6-Dimethylphenyl)oxy]-1-methylethyl]aminehydrochloride

Suppliers and Price of (+)-(S)-Mexiletine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
S-(+)-MexiletineHydrochloride
50mg
$ 110.00

Crysdot
(S)-1-(2,6-Dimethylphenoxy)propan-2-aminehydrochloride 97%
1g
$ 1292.00

AK Scientific
(S)-1-(2,6-DIMETHYLPHENOXY)PROPAN-2-AMINEHCL
250mg
$ 810.80

AK Scientific
(S)-1-(2,6-DIMETHYLPHENOXY)PROPAN-2-AMINEHCL
100mg
$ 507.20

Total 5 raw suppliers

Chemical Property of (+)-(S)-Mexiletine hydrochloride

Chemical Property:

PSA：35.25000
LogP:3.53170
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, Methanol

Purity/Quality:

99% ^*data from raw suppliers

S-(+)-MexiletineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses The S-enantiomer of Mexiletine (M340800). Antiarrhythmic (class IB).

Technology Process of (+)-(S)-Mexiletine hydrochloride

There total 5 articles about (+)-(S)-Mexiletine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: (R)-N-(1-(2,6-dimethylphenoxy)propan-2-yl)-tert-butanesulfinamide

: 81771-85-9
(+)-Mexiletine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane;
DOI:10.1016/j.tetlet.2015.05.041

Reference yield:

: 53012-41-2
(2,6-dimethylphenoxy)-2-propanone

: 81771-85-9
(+)-Mexiletine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: titanium(IV) tetraethanolate / neat (no solvent) / 1 h / Microwave irradiation; Sealed tube

2: L-Selectride / tetrahydrofuran / 5 h / -45 °C

3: hydrogenchloride / 1,4-dioxane

With hydrogenchloride; titanium(IV) tetraethanolate; L-Selectride; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.tetlet.2015.05.041

Reference yield:

: C₁₅H₂₃NO₂S

: 81771-85-9
(+)-Mexiletine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: L-Selectride / tetrahydrofuran / 5 h / -45 °C

2: hydrogenchloride / 1,4-dioxane

With hydrogenchloride; L-Selectride; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.tetlet.2015.05.041