N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

Base Information

• Chemical Name: N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine
• CAS No.: 619276-03-8
• Molecular Formula: C₃₉H₃₁N₅O₈
• Molecular Weight: 697.704

Synonyms:N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

Chemical Property of N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

There total 7 articles about N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

benzoyl chloride (98-88-4) + N6-benzoyl-(2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine (222849-02-7) → N6-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine (619276-03-8)

Guidance literature:

In pyridine; at 0 ℃; for 0.5h;

DOI:10.1002/hlca.200390118

Reference yield:

N-benzoyladenine (4005-49-6) → N6-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine (619276-03-8)

Guidance literature:

Multi-step reaction with 6 steps

1.1: BSA / acetonitrile / 1.5 h / 65 °C

1.2: 84 percent / SnCl₄ / acetonitrile / 1.5 h / 65 °C

2.1: 88 percent / NaOH / methanol; H₂O / 1.25 h / -20 °C

3.1: 87 percent / TsOH*H₂O / dimethylformamide / 0.5 h / 4 °C

4.1: 76 percent / pyridine; CH₂Cl₂ / 20 °C

5.1: 70 percent / acetic acid; H₂O / 48 h / 40 °C

6.1: 73 percent / pyridine / 0.5 h / 0 °C

With benzenesulfonamide; sodium hydroxide; toluene-4-sulfonic acid; In pyridine; methanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/hlca.200390118

Reference yield:

9-(α-L-arabinopyranosyl)-N6-benzoyl-adenine (222848-92-2) → N6-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine (619276-03-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 87 percent / TsOH*H₂O / dimethylformamide / 0.5 h / 4 °C

2: 76 percent / pyridine; CH₂Cl₂ / 20 °C

3: 70 percent / acetic acid; H₂O / 48 h / 40 °C

4: 73 percent / pyridine / 0.5 h / 0 °C

With toluene-4-sulfonic acid; In pyridine; dichloromethane; water; acetic acid; N,N-dimethyl-formamide;

DOI:10.1002/hlca.200390118

upstream raw materials:

benzoyl chloride

N⁶-benzoyl-(2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

N-benzoyladenine

N⁶-benzoyl-9-(3',4'-O-isopropylidene-α-L-arabinopyranosyl)adenine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 619276-03-8 N⁶-benzoyl-9-(3'-O-benzoyl-2'-O-{[(9H-fluoren-9-yl)methoxy]carbonyl}-α-L-arabinopyranosyl)adenine

Send

Send

Metric Ton KG G Pound L ML

Send

Send