R-METHYLCARVONE

Base Information

• Chemical Name: R-METHYLCARVONE
• CAS No.: 85710-65-2
• Molecular Formula: C11H16 O
• Molecular Weight: 0
• Mol file: 85710-65-2.mol

Synonyms:2-Cyclohexen-1-one,2,3-dimethyl-5-(1-methylethenyl)-, (R)-; (R)-3-Methylcarvone

Chemical Property of R-METHYLCARVONE

Chemical Property:

• PSA: 17.07000
• LogP: 2.87800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of R-METHYLCARVONE

There total 11 articles about R-METHYLCARVONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl magnesium iodide (917-64-6) + (R)-Carvone (6485-40-1,2244-16-8) → (5S)-2,3-Dimethyl-5-isopropenylcyclohex-2-en-1-one (85710-65-2,85710-66-3)

Guidance literature:

methyl magnesium iodide; (R)-Carvone; In diethyl ether; at 0 - 20 ℃; for 1h;

With silica gel; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1016/j.tetasy.2005.07.030

Reference yield: 92.0%

(-)-(1S,4S,6S)-4-isopropenyl-1,6-dimethyl-7-oxabicyclo[4.1.0]heptan-2-one (143612-00-4) → (5S)-2,3-Dimethyl-5-isopropenylcyclohex-2-en-1-one (85710-65-2,85710-66-3)

Guidance literature:

With sodium hydroxide; thiourea dioxide; tetrabutylammomium bromide; In tetrahydrofuran; at 50 ℃; for 0.5h;

DOI:10.1016/S0040-4039(96)02451-3

Reference yield: 90.0%

(R)-5-Isopropenyl-7a-methyl-3,3a,4,5,6,7a-hexahydro-indazol-7-one (127841-75-2) → (R)-2,3-dimethyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one (85710-65-2)

Guidance literature:

In ethylene glycol; for 0.25h; Heating;

upstream raw materials:

1,2-dimethyl-5-(1-methylethenyl)cyclohex-2-en-1-ol

(R)-5-Isopropenyl-7a-methyl-3,3a,4,5,6,7a-hexahydro-indazol-7-one

(S)-p-mentha-6,8-dien-2-one

diazomethane

Downstream raw materials:

(5R)-5-(1-Chloro-1-methylethyl)-2,3-dimethylcyclohex-2-en-1-one

(5S)-5-(1-Chloro-1-methylethyl)-2,3-dimethylcyclohex-2-en-1-one

(+)-(S)-2,3-dimethyl-5-(2-bromoprop-2-yl)-cyclohex-2-en-1-one

(1S,5S)-5-Isopropenyl-2,3-dimethylcyclohex-2-en-1-ol