6-hydroxychroman-2-carboxylic Acid

Base Information

Chemical Name:6-hydroxychroman-2-carboxylic Acid
CAS No.:81498-19-3
Molecular Formula:C₁₀H₁₀O₄
Molecular Weight:194.187
Hs Code.:
DSSTox Substance ID:DTXSID10465409
Mol file:81498-19-3.mol

Synonyms:81498-19-3;6-hydroxychroman-2-carboxylic Acid;6-hydroxy-3,4-dihydro-2H-chromene-2-carboxylic acid;6-HYDROXY-3,4-DIHYDRO-2H-1-BENZOPYRAN-2-CARBOXYLIC ACID;2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-;2H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 3,4-DIHYDRO-6-HYDROXY-;6-hydroxychroman-2-carboxylic;SCHEMBL4193774;2h-1-benzopyran-2-carboxylic acid,3,4-dihydro-6-hydroxy-;DTXSID10465409;OEPFJOJFTVSOOI-UHFFFAOYSA-N;AKOS006288549;AB45863;(RS)-6-hydroxy-chroman-2-carboxylic acid;D78640;3,4-DIHYDRO-6-HYDROXY-2H-1-BENZOPYRAN-2-CARBOXYLIC ACID

Suppliers and Price of 6-hydroxychroman-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,4-DIHYDRO-6-HYDROXY-2H-1-BENZOPYRAN-2-CARBOXYLIC ACID 95.00%
5MG
$ 497.46

Total 4 raw suppliers

Chemical Property of 6-hydroxychroman-2-carboxylic Acid

Chemical Property:

PSA：66.76000
LogP:1.17040
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:194.05790880
Heavy Atom Count:14
Complexity:228

Purity/Quality:

98%min ^*data from raw suppliers

3,4-DIHYDRO-6-HYDROXY-2H-1-BENZOPYRAN-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)O)OC1C(=O)O

Technology Process of 6-hydroxychroman-2-carboxylic Acid

There total 2 articles about 6-hydroxychroman-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 99199-69-6
(RS)-6-methoxy-chroman-2-carboxylic acid

: 81498-19-3
(RS)-6-hydroxy-chroman-2-carboxylic acid

Guidance literature:: With pyridine hydrochloride; at 180 ℃; for 2h;

Reference yield:

: 86277-98-7
6-methoxy-4-oxo-4H-1-benzopyran-2-carboxylic acid

: 81498-19-3
(RS)-6-hydroxy-chroman-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 10% palladium on activated carbon / acetic acid / 5 h / 60 °C

2: pyridine hydrochloride / 2 h / 180 °C

With hydrogen; pyridine hydrochloride; 10% palladium on activated carbon; In acetic acid;

Reference yield: 60.0%

: 81498-19-3
(RS)-6-hydroxy-chroman-2-carboxylic acid

: 100-39-0
benzyl bromide

: (RS)-6-benzyloxy-(chroman-2-yl)-methanol

Guidance literature:: (RS)-6-hydroxy-chroman-2-carboxylic acid; With lithium aluminium tetrahydride; In tetrahydrofuran; for 0.25h;

With hydrogenchloride; In water; ethyl acetate;

benzyl bromide; With potassium carbonate; In acetone; for 18h; Heating / reflux;