4-Chloro-2,6-bis(trifluoromethyl)pyridine

Base Information

Chemical Name:4-Chloro-2,6-bis(trifluoromethyl)pyridine
CAS No.:81269-96-7
Molecular Formula:C7H2 Cl F6 N
Molecular Weight:249.543
Hs Code.:2933399090
European Community (EC) Number:873-310-4
DSSTox Substance ID:DTXSID20513581
Wikidata:Q82373469
Mol file:81269-96-7.mol

Synonyms:4-Chloro-2,6-bis(trifluoromethyl)pyridine;81269-96-7;MFCD00082558;2,6-Bis(trifluoromethyl)-4-chloropyridine;4-CHLORO-2,6-BIS(TRIFLUOROMETHYL)PYRIDINE);SCHEMBL1965945;DTXSID20513581;AKOS005258900;AB03097;CS-0314534;FT-0681963;EN300-6225485;10Z-7005;J-514922

Suppliers and Price of 4-Chloro-2,6-bis(trifluoromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2,6-Bis(trifluoromethyl)-4-chloropyridine
1 g
$ 797.00

SynQuest Laboratories
2,6-Bis(trifluoromethyl)-4-chloropyridine
500 mg
$ 592.00

Matrix Scientific
4-Chloro-2,6-bis(trifluoromethyl)pyridine >95%
500mg
$ 307.00

Matrix Scientific
4-Chloro-2,6-bis(trifluoromethyl)pyridine >95%
1g
$ 473.00

Crysdot
4-Chloro-2,6-bis(trifluoromethyl)pyridine 95+%
1g
$ 468.00

Apolloscientific
2,6-Bis(trifluoromethyl)-4-chloropyridine
500mg
$ 370.00

Apolloscientific
2,6-Bis(trifluoromethyl)-4-chloropyridine
1g
$ 498.00

Alichem
2,6-Bis(trifluoromethyl)-4-chloropyridine
5g
$ 2748.71

Alichem
2,6-Bis(trifluoromethyl)-4-chloropyridine
1g
$ 639.24

AK Scientific
4-Chloro-2,6-bis(trifluoromethyl)pyridine
1g
$ 688.00

Total 7 raw suppliers

Chemical Property of 4-Chloro-2,6-bis(trifluoromethyl)pyridine

Chemical Property:

Vapor Pressure:22.3mmHg at 25°C
Refractive Index:1.4
Boiling Point:115.8°C at 760 mmHg
PKA:-5.76±0.10(Predicted)
Flash Point:23.8°C
PSA：12.89000
Density:1.543g/cm³
LogP:3.77260
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:248.9779957
Heavy Atom Count:15
Complexity:203

Purity/Quality:

98%min ^*data from raw suppliers

2,6-Bis(trifluoromethyl)-4-chloropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(N=C1C(F)(F)F)C(F)(F)F)Cl

Technology Process of 4-Chloro-2,6-bis(trifluoromethyl)pyridine

There total 1 articles about 4-Chloro-2,6-bis(trifluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-chloro-2,6-bis(trichloromethyl)pyridine

: 7783-56-4
antimony(III) fluoride

: 81269-96-7
4-Chloro-2,6-bis(trifluoromethyl)pyridine

Guidance literature:: With hydrogenchloride;

Reference yield: 50.0%

: 128-39-2
2,6-di-tert-butylphenol

: 81269-96-7
4-Chloro-2,6-bis(trifluoromethyl)pyridine

: 139218-73-8
2,6-Bis(trifluoromethyl)-4-(3',5'-di-tert-butyl-4'-hydroxyphenyl)pyridine

Guidance literature:: With terephthalonitrile; potassium tert-butylate; In ammonia; at -38 ℃; electrosynthesis: cathode - platinum grid, 10 cm², 1024 mesh/cm²; anode - magnesium rod, h = 8 cm, Φ = 1 cm; constant current density 0,5 A dm^-2, KBr as supporting electrolyte;
DOI:10.1021/jo00095a024

Reference yield:

: C₁₈H₁₈O₃

: 81269-96-7
4-Chloro-2,6-bis(trifluoromethyl)pyridine

: C₂₅H₂₁F₆NO₃

Guidance literature:: With tetrabutyl-ammonium chloride; potassium formate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; copper(l) iodide; In N,N-dimethyl-formamide; at 150 ℃; for 0.5h; Microwave irradiation;