4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TO LUIDINE HYDROCHLORIDE, 98

Base Information

• Chemical Name: 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TO LUIDINE HYDROCHLORIDE, 98
• CAS No.: 80997-89-3
• Molecular Formula: C₇H₅BrF₃N*ClH
• Molecular Weight: 276.484
• Mol file: 80997-89-3.mol

Synonyms:Benzenamine,4-bromo-2-(trifluoromethyl)-, hydrochloride (9CI)

Chemical Property of 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TO LUIDINE HYDROCHLORIDE, 98

Chemical Property:

• Vapor Pressure: 0.0137mmHg at 25°C
• Melting Point: 167 °C (dec.)(lit.)
• Boiling Point: 254.4°C at 760 mmHg
• Flash Point: 107.6°C
• PSA: 26.02000
• LogP: 4.43330

Purity/Quality:

99%min ^*data from raw suppliers

2-Amino-5-bromobenzotrifluoridehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TO LUIDINE HYDROCHLORIDE, 98

There total 1 articles about 4-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TO LUIDINE HYDROCHLORIDE, 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

4-bromo-1-nitro-2-(trifluoromethyl)benzene (344-38-7) → 4-bromo-2-trifluoromethylaniline hydrochloride (1214372-39-0,80997-89-3)

Guidance literature:

4-bromo-1-nitro-2-(trifluoromethyl)benzene; With iron(III) acetylacetonate; 1,1,3,3-Tetramethyldisiloxane; In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere; Sealed tube;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; for 0.0833333h;

DOI:10.1016/j.tet.2010.12.070

Reference yield:

N-Cyanoguanidine (127099-85-8,780722-26-1,461-58-5) + 4-bromo-2-trifluoromethylaniline hydrochloride (1214372-39-0,80997-89-3) → 1-(4-Brom-2-trifluormethylphenyl)-biguanid

Guidance literature:

upstream raw materials:

4-bromo-1-nitro-2-(trifluoromethyl)benzene

Refernces