di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate

Base Information

• Chemical Name: di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate
• CAS No.: 1427381-20-1
• Molecular Formula: C₃₃H₅₈N₂O₇Si
• Molecular Weight: 622.918
• Mol file: 1427381-20-1.mol

Synonyms:di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate

Chemical Property of di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate

There total 1 articles about di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) + tert-butyldimethylsilyl chloride (18162-48-6) + N-(2-hydroxybenzyl)-1,2-diaminoethane (60067-50-7) → di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate (1427381-20-1)

Guidance literature:

tert-butyldimethylsilyl chloride; N-(2-hydroxybenzyl)-1,2-diaminoethane; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere; Cooling with ice;

bromoacetic acid tert-butyl ester; In dichloromethane; at 0 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ja312610j

Reference yield: 100.0%

di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((tert-butyldimethylsilyl)oxy)-benzyl)amino)ethyl)azanediyl)diacetate (1427381-20-1) → 2,2'-((2-((carboxymethyl)(2-hydroxybenzyl)amino)ethyl)azanediyl)diacetic acid (112827-80-2)

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; 1-dodecylthiol; In water; for 5h;

DOI:10.1021/ja312610j

upstream raw materials:

bromoacetic acid tert-butyl ester

tert-butyldimethylsilyl chloride

N-(2-hydroxybenzyl)-1,2-diaminoethane

Downstream raw materials:

2,2'-((2-((carboxymethyl)(2-hydroxybenzyl)amino)ethyl)azanediyl)diacetic acid