Technology Process of methyl 2-benzyl-3-(furan-2-yl)propanoate
There total 6 articles about methyl 2-benzyl-3-(furan-2-yl)propanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethanol;
for 5h;
DOI:10.1021/ol402163u
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
1.2: 15 h / 60 °C
2.1: sodium tetrahydroborate / ethanol / 5 h / -78 °C
3.1: triethylamine / dichloromethane / 15 h / 0 - 20 °C / Inert atmosphere
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 15 h / 20 °C
5.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h
With
sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/ol402163u
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere
1.2: 15 h / 60 °C
2.1: sodium tetrahydroborate / ethanol / 5 h / -78 °C
3.1: triethylamine / dichloromethane / 15 h / 0 - 20 °C / Inert atmosphere
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 15 h / 20 °C
5.1: palladium 10% on activated carbon; hydrogen / ethanol / 5 h
With
sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/ol402163u
