methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate

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Chemical Name:methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate
CAS No.:1426324-09-5
Molecular Formula:C₂₃H₂₉F₃N₂O₅
Molecular Weight:470.489
Hs Code.:

Synonyms:methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate

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Chemical Property of methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate

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Technology Process of methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate

There total 1 articles about methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 4070-48-8
L-Valine methyl ester

: 1426324-05-1
1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropanecarboxylic acid

: 1426324-09-5
methyl N-({1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)-L-valinate

Guidance literature:: 1-[(2R,3S)-3-(benzyloxy)-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropanecarboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.333333h;

L-Valine methyl ester; With triethylamine; In dichloromethane; at 20 ℃; for 23h;
DOI:10.1007/s00726-012-1401-0