(N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine

Base Information

Chemical Name:(N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine
CAS No.:1228430-46-3
Molecular Formula:C₂₀H₂₀F₃N₃O₂S
Molecular Weight:423.459
Hs Code.:

Synonyms:(N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine

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Chemical Property of (N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine

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Technology Process of (N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine

There total 1 articles about (N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1228430-45-2
(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]heptane-4-carbaldehyde

: 74784-70-6
2-amino-5-trifluoromethylpyridine

: 1228430-46-3
(N-(1E)-{(1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]hept-4-yl}methylidene)-5-(trifluoromethyl)-2-pyridinamine

Guidance literature:: (1R,4S,6R)-3-[(4-methylphenyl)sulfonyl]-3-azabicyclo[4.1.0]heptane-4-carbaldehyde; 2-amino-5-trifluoromethylpyridine; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; for 2h;