C₁₆H₁₇⁽²⁾HO₃

Base Information

• Chemical Name: C₁₆H₁₇⁽²⁾HO₃
• CAS No.: 1207730-42-4
• Molecular Formula: C₁₆H₁₈O₃
• Molecular Weight: 259.309
• Mol file: 1207730-42-4.mol

Synonyms:C₁₆H₁₇⁽²⁾HO₃

Chemical Property of C₁₆H₁₇⁽²⁾HO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₆H₁₇⁽²⁾HO₃

There total 2 articles about C₁₆H₁₇⁽²⁾HO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C21H37(2)HO2Sn (1207730-41-3) + benzaldehyde (100-52-7) → C16H17(2)HO3 (1207730-42-4)

Guidance literature:

C₂₁H₃₇⁽²⁾HO₂Sn; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; diethyl ether; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; hexane; water; at -78 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.11.084

Reference yield: 61.0%

C21H37(2)HO2Sn (1207730-41-3) + benzaldehyde (100-52-7) → C9H11(2)HO2 (1207730-43-5) + C16H17(2)HO3 (1207730-42-4)

Guidance literature:

C₂₁H₃₇⁽²⁾HO₂Sn; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; for 0.166667h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; diethyl ether; hexane; at -50 ℃; for 0.166667h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; hexane; water; at -50 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.11.084

Reference yield: 81.0%

C16H17(2)HO3 (1207730-42-4) → (2R)-1-phenyl[2-D1]ethane-1,2-diol

Guidance literature:

C₁₆H₁₇⁽²⁾HO₃; With chloro-trimethyl-silane; methoxybenzene; tin(ll) chloride; In dichloromethane; at 20 ℃; for 1.5h;

With water; sodium hydrogencarbonate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2009.11.084

upstream raw materials:

C₂₁H₃₇⁽²⁾HO₂Sn

benzaldehyde

Downstream raw materials:

C₂₆H₂₄⁽²⁾HF₃O₅