Technology Process of C24H39NO3Si
There total 4 articles about C24H39NO3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C18H25NO3;
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
at -78 ℃;
for 0.0833333h;
Molecular sieve;
Inert atmosphere;
tert-butyldimethylsilyl chloride;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 5h;
Molecular sieve;
Inert atmosphere;
DOI:10.1021/ol4034447
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium hexamethylsilazane; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 18 h / -78 - 20 °C / Inert atmosphere
2.1: potassium hexamethylsilazane; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
2.2: 18 h / -78 - 20 °C / Inert atmosphere
3.1: potassium hexamethylsilazane / tetrahydrofuran / 0.08 h / -78 °C / Molecular sieve; Inert atmosphere
3.2: 5 h / -78 - 20 °C / Molecular sieve; Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane;
In
tetrahydrofuran;
DOI:10.1021/ol4034447
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium hexamethylsilazane; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 18 h / -78 - 20 °C / Inert atmosphere
2.1: potassium hexamethylsilazane / tetrahydrofuran / 0.08 h / -78 °C / Molecular sieve; Inert atmosphere
2.2: 5 h / -78 - 20 °C / Molecular sieve; Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane;
In
tetrahydrofuran;
DOI:10.1021/ol4034447
