bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

Base Information

Chemical Name:bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate
CAS No.:1383741-14-7
Molecular Formula:C₅₈H₇₂Cl₄N₆O₈
Molecular Weight:1123.06
Hs Code.:

Synonyms:bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

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Chemical Property of bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

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Technology Process of bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

There total 2 articles about bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111-19-3
sebacoyl chloride

: 1259312-25-8
7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-1-(hydroxymethyl)-3,4-dihydroquinolin-2-(1H )-one

: 1383741-14-7
bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

Guidance literature:: With triethylamine; In dichloromethane; at 25 - 45 ℃; Inert atmosphere;

Reference yield:

: 129722-12-9
aripiprazole

: 1383741-14-7
bis((7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydro-quinolin-1(2H)-yl)methyl) decanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide; water / 48 h / 80 °C

2: triethylamine / dichloromethane / 25 - 45 °C / Inert atmosphere

With triethylamine; In dichloromethane; water; N,N-dimethyl-formamide;