ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

Base Information

Chemical Name:ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate
CAS No.:639784-48-8
Molecular Formula:C₁₅H₂₀F₃NO₃
Molecular Weight:319.324
Hs Code.:

Synonyms:ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

Suppliers and Price of ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

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Technology Process of ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

There total 1 articles about ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.9%

: 51336-35-7
α-(4-formylphenoxy)isobutyric acid ethyl ester

: 639784-48-8
ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

Guidance literature:: With sodium triacetoxy borohydride; trifluoroethylamine; In dichloromethane; at 25 ℃; for 12h;

Reference yield: 69.92%

: 639784-48-8
ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

: 639783-70-3
Example 42

Guidance literature:: With potassium carbonate; 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole; for 1h;

Reference yield:

: 639784-48-8
ETHYL-2-METHYL-2-[(4-(N-(2,2,2-trifluoroethyl)aminomethyl)phenoxy)]-propanoate

: 639783-87-2
2-METHYL-2-[4-{[(4-METHYL-2-[4-TRIFLUOROMETHYL PHENYL]-THIAZOL-5-YLMETHYL)-N-(2, 2, 2-TRIFLUOROETHYL)-AMINO]METHYL}PHENOXY]PROPIONIC ACID

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole / 1 h

2: sodium hydroxide / 12 h / 60 °C

With sodium hydroxide; potassium carbonate; 5-(chloromethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole;