methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside]

Base Information

• Chemical Name: methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside]
• CAS No.: 120200-52-4
• Molecular Formula: C₁₆H₂₂O₆
• Molecular Weight: 310.347
• Mol file: 120200-52-4.mol

Synonyms:methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside]

Chemical Property of methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside]

There total 54 articles about methyl-[O⁴,O⁶-((R)-benzylidene-O²,O³-dimethyl-α-D-altropyranoside] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.2%

4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside (3162-96-7) + methyl iodide (74-88-4) → methyl 4,6-O-benzylidene-2,3-di-O-methyl-α,D-glucopyranoside (3013-58-9,3051-89-6,4261-46-5,6748-99-8,13035-20-6,13502-46-0,22893-88-5,35311-32-1,53767-28-5,56586-53-9,56586-54-0,69744-11-2,94480-09-8,120200-48-8,120200-49-9,120200-50-2,120200-52-4)

Guidance literature:

4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 1h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;

DOI:10.1016/j.bmcl.2017.06.008

Reference yield: 95.0%

methyl 4,6-O-benzylidene-α-D-glucopyranoside (3162-96-7) + methyl iodide (74-88-4) → methyl 4,6-O-benzylidene-2,3-di-O-methyl-α-D-glucopyranoside (3013-58-9,3051-89-6,4261-46-5,6748-99-8,13035-20-6,13502-46-0,22893-88-5,35311-32-1,53767-28-5,56586-53-9,56586-54-0,69744-11-2,94480-09-8,120200-48-8,120200-49-9,120200-50-2,120200-52-4)

Guidance literature:

methyl 4,6-O-benzylidene-α-D-glucopyranoside; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 1.33333h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 20.5h;

DOI:10.1021/ja402319m

Reference yield: 88.0%

methyl 4,6-O-benzylidene-α-D-glucopyranoside (3162-96-7) + methyl iodide (74-88-4) → methyl 4,6-O-benzylidene-2,3-di-O-methyl-α,D-glucopyranoside (3013-58-9,3051-89-6,4261-46-5,6748-99-8,13035-20-6,13502-46-0,22893-88-5,35311-32-1,53767-28-5,56586-53-9,56586-54-0,69744-11-2,94480-09-8,120200-48-8,120200-49-9,120200-50-2,120200-52-4)

Guidance literature:

methyl 4,6-O-benzylidene-α-D-glucopyranoside; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.333333h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 16h;

upstream raw materials:

Methyl 2,3-anhydro-4,6-O-(phenylmethylene)-β-D-allopyranoside

4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside

benzylidene dichloride

methyl 2,3-di-O-methyl-α-D-glucopyranoside

Downstream raw materials:

methyl 2,3-di-O-methyl-α-D-glucopyranoside

methyl 6-O-benzyl-2,3-di-O-methyl-α-D-glucopyranoside

methyl 4-O-benzyl-2,3-di-O-methyl-α-D-glucopyranoside

methyl 6-O-benzoyl-2,3-di-O-methyl-α-D-glucopyranoside