4-bromo-3-chlorobenzoyl chloride

Base Information

• Chemical Name: 4-bromo-3-chlorobenzoyl chloride
• CAS No.: 21900-32-3
• Molecular Formula: C₇H₃BrCl₂O
• Molecular Weight: 253.91
• Mol file: 21900-32-3.mol

Synonyms:4-bromo-3-chlorobenzoyl chloride

Chemical Property of 4-bromo-3-chlorobenzoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-3-chlorobenzoyl chloride

There total 4 articles about 4-bromo-3-chlorobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-3-chlorobenzoic acid (25118-59-6) → 4-bromo-3-chlorobenzoyl chloride (21900-32-3)

Guidance literature:

With phosphorus pentachloride; at 130 - 140 ℃;

Reference yield:

1-bromo-2-chloro-4-methylbenzene (6627-51-6) → 4-bromo-3-chlorobenzoyl chloride (21900-32-3)

Guidance literature:

Multi-step reaction with 2 steps

1: HNO₃

2: PCl₅ / 130 - 140 °C

With phosphorus pentachloride; nitric acid;

Reference yield:

2-chloro-4-methyl-benzenamine (615-65-6) → 4-bromo-3-chlorobenzoyl chloride (21900-32-3)

Guidance literature:

Multi-step reaction with 3 steps

2: HNO₃

3: PCl₅ / 130 - 140 °C

With phosphorus pentachloride; nitric acid;

upstream raw materials:

4-bromo-3-chlorobenzoic acid

1-bromo-2-chloro-4-methylbenzene

2-chloro-4-methyl-benzenamine

Downstream raw materials:

7-bromo-6-chloro-3,4-dihydroquinazolin-4-one

C₁₂H₉BrClNO

Refernces

• 1、 Sijm, Maarten,Sterk, Geert Jan,Caljon, Guy,Maes, Louis,de Esch, Iwan J. P.,Leurs, Rob. "Structure-Activity Relationship of Phenylpyrazolones against Trypanosoma cruzi". supporting information. p. 1310 - 1321. Retrieved 2020/05/08.
• 2、 -. "CYCLIC AMIDE DERIVATIVE". Paragraph 0350; 0351; 0352. . Retrieved 2013/07/25.