N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester

Base Information

Chemical Name:N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester
CAS No.:27483-27-8
Molecular Formula:C₂₅H₃₇N₃O₆
Molecular Weight:475.585
Hs Code.:
DSSTox Substance ID:DTXSID601129091

Synonyms:DTXSID601129091;N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester;27483-27-8

Suppliers and Price of N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:475.26823591
Heavy Atom Count:34
Complexity:727

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)N1CCCC1C(=O)N(C)CC(=O)OC(C)(C)C)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)[C@H](C(=O)N1CCC[C@H]1C(=O)N(C)CC(=O)OC(C)(C)C)NC(=O)OCC2=CC=CC=C2

Technology Process of N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester

There total 4 articles about N-[(Phenylmethoxy)carbonyl]-D-valyl-L-prolyl-N-methylglycine 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5616-81-9
sarcosine tert-butyl ester

: 27483-27-8
N-(benzyloxycarbonyl)-D-valylprolylsarcosine tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: DCC / CH₂Cl₂ / -10 °C

2: H₂ / 10percent Pd/C / methanol / 2 h / 760 Torr

3: DCC / CH₂Cl₂ / -10 °C

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja00085a002

Reference yield:

: 5616-82-0
N-(benzyloxycarbonyl)prolylsarcosine tert-butyl ester

: 27483-27-8
N-(benzyloxycarbonyl)-D-valylprolylsarcosine tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / methanol / 2 h / 760 Torr

2: DCC / CH₂Cl₂ / -10 °C

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja00085a002

Reference yield:

: 101644-79-5
α-tert-butyl N-(benzyloxycarbonyl)-N-methylglycinate

: 27483-27-8
N-(benzyloxycarbonyl)-D-valylprolylsarcosine tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / methanol / 2 h / 760 Torr

2: DCC / CH₂Cl₂ / -10 °C

3: H₂ / 10percent Pd/C / methanol / 2 h / 760 Torr

4: DCC / CH₂Cl₂ / -10 °C

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/ja00085a002